摘要
目的研究维生素D联合“双C”方案治疗妊娠期糖尿病的临床效果。方法选取2023年1—12月东平县人民医院产科收治的66例妊娠期糖尿病患者为研究对象,按照治疗方案的不同分为对照组和观察组,各33例。对照组实施皮下注射胰岛素治疗,观察组实施维生素D联合“双C”方案治疗。对比两组患者血糖达标时间、住院时间、空腹血糖、餐后2 h血糖、胰岛素抵抗指数及不良母婴结局发生率。结果治疗后,观察组血糖达标时间与住院时间短于对照组,空腹血糖、餐后2 h血糖及胰岛素抵抗指数均低于对照组,差异有统计学意义(P均<0.05)。观察组不良母婴结局(低血糖、早产儿、巨大儿、新生儿窒息、低出生体重儿)发生率均低于对照组,差异有统计学意义(P均<0.05)。结论在妊娠期糖尿病临床治疗中,维生素D与“双C”方案联合治疗可起到平稳控制血糖的作用,同时有利于降低不良母婴结局发生率,对新生儿预后有利,并且安全性、有效性较高。
Objective To study the clinical effect of vitamin D combined with"double C"regimen in the treatment of gestational diabetes mellitus.Methods A total of 66 patients with gestational diabetes mellitus admitted to the Department of Obstetrics of Dong Ping Xian Ren Min Yi Yuan from January to December 2023 were selected as the research objects.According to different treatment schemes,they were divided into control group and observation group,with 33 cases in each group.The control group was treated with subcutaneous injection of insulin,and the observation group was treated with vitamin D combined with"double C"regimen.The blood glucose standard time,hospitalization time,fasting blood glucose,2-hour postprandial blood glucose and homeostatic model assessment of insulin resistance and the incidence of adverse maternal and infant outcomes were compared between the two groups.Results After treatment,the blood glucose standard time and hospitalization time of the observation group were shorter than those of the control group,the fasting blood glucose,2-hour postprandial blood glucose and homeostatic model assessment of insulin resistance were lower than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse maternal and infant outcomes(hypoglycemia,premature infants,macrosomia and neonatal asphyxia,low birth weight infant)in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion In the clinical treatment of gestational diabetes mellitus,the combination of vitamin D and"double C"can play a role in stabilizing blood glucose,while helping to reduce the incidence of adverse maternal and infant outcomes,and is beneficial to newborn prognosis,with high safety and effectiveness.
作者
隋艳芬
王恩如
王永华
SUI Yanfen;WANG Enru;WANG Yonghua(Department of Obstetrics,Dong Ping Xian Ren Min Yi Yuan,Tai'an 271500,Shandong,China)
出处
《糖尿病新世界》
2024年第16期74-76,87,共4页
Diabetes New World
关键词
维生素D
“双C”方案
妊娠期糖尿病
胰岛素
血糖水平
母婴结局
Vitamin D
"Double C"scheme
Gestational diabetes mellitus
Insulin
Blood glucose levels
Maternal and infant outcome
