摘要
目的探究全胃癌患者采用不同照射技术放疗的效果。方法选择全胃癌患者80例,依据照射技术的不同分为观察组(三维适形放疗技术)及对照组(简单调强技术),各40例。比较两组格拉斯哥昏迷评分法(GCS)评分、生存质量评分、临床疗效、不良反应发生情况等。结果两组放疗前GCS评分比较无意义(P>0.05);放疗后,观察组GCS评分(13.10±1.86)分高于对照组的(11.15±1.91)分,差异有统计学意义(P<0.05)。观察组社会关系、生理、环境、心理评分分别为(27.55±5.18)、(25.36±5.41)、(24.67±5.43)、(24.50±5.47)分,高于对照组的(18.20±4.26)、(17.25±4.11)、(17.28±4.14)、(17.26±4.91)分,差异有统计学意义(P<0.05)。观察组总有效率为95.00%,高于对照组的70.00%,差异有统计学意义(P<0.05)。观察组不良反应发生率为2.50%,低于对照组的22.50%,差异有统计学意义(P<0.05)。结论将三维适形放疗技术用于全胃癌患者的治疗,能明显改善患者疾病预后,提升生存质量,减少不良反应,提升对全胃癌的治疗效果,适合应用于临床推广。
Objective To explore the effect of different irradiation techniques in patients with total gastric cancer.Methods 80 patients with total gastric cancer were selected and subdivided into an observation group(three-dimensional conformal radiotherapy)and a control group(simple intensity modulation technique)according to different irradiation techniques,each with 40 cases.The Glasgow coma scale(GCS)score,quality of life score,clinical efficacy,and occurrence of adverse reactions were compared between two groups.Results There was no significant difference in GCS scores between the two groups before radiotherapy(P>0.05).After radiotherapy,GCS score of(13.10±1.86)points in the observation group was higher than(11.15±1.91)points in the control group,and the difference was statistically significant(P<0.05).The scores of social relation,physiology,environment and psychology in the observation group were(27.55±5.18),(25.36±5.41),(24.67±5.43)and(24.50±5.47)points,which were higher than(18.20±4.26),(17.25±4.11),(17.28±4.14)and(17.26±4.91)points in the control group,and the difference was statistically significant(P<0.05).The total effective rate of 95.00%in the observation group was higher than 70.00%in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of 2.50%in the observation group was lower than 22.50%in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of three-dimensional conformal radiotherapy in the treatment of patients with total gastric cancer can significantly improve the prognosis of patients,improve the quality of life,reduce the occurrence of adverse reactions,and enhance the therapeutic effect of total gastric cancer,which is suitable for clinical promotion.
作者
邹勇斌
ZOU Yong-bin(Third Department of Medical Oncology,Chenzhou No.1 People's Hospital,Chenzhou 423000,China)
出处
《中国实用医药》
2024年第20期50-53,共4页
China Practical Medicine
基金
郴州市技术研发中心项目(项目编号:2020-27号)。
关键词
全胃癌
照射技术
放疗
三维适形放疗
Total gastric cancer
Irradiation techniques
Efficacy evaluation
Three-dimensional conformal radiotherapy
