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梅毒诊断中三种梅毒血清学检测方法的对比分析

Comparative Analysis of Three Serological Detection Methods in Diagnosis of Syphilis
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摘要 目的 分析对比梅毒诊断中三种梅毒血清学检测方法的结果及应用价值。方法 选取2021年12月—2022年12月本单位收集的200例梅毒血清样本进行对比分析,采用快速梅毒螺旋体抗体胶体金法、梅毒螺旋体明胶凝集试验(TPPA)以及甲苯胺红不加热血清反应素试验(TRUST)三种梅毒血清学检测方法,对200例样本进行对比分析,探讨其检测准确性。结果 ①TPPA与TRUST检测方法相对比,TPPA检出率显著增高(P<0.05);②TRUST与胶体金法检测方法相对比,胶体金法检测方法检出率更高(P<0.05);③TPPA与胶体金法检测方法相对比,检出准确率差异无统计学意义(P>0.05)。结论 在梅毒疾病的诊断过程中,采用胶体金法及梅毒螺旋体明胶凝集试验作为检测手段,能够有效地检测出梅毒疾病,展现出较高的检出率,因此具备显著的临床应用价值。 Objective To analyze and compare effect and application value of three serological detection methods in diagnosis of syphilis.Methods The paper carried on comparative analysis on 200 syphilis serum samples collected from December 2021 to December 2022.200 samples were compared and analyzed with three syphilis serological detection methods,including rapid treponema pallidum antibody colloidal gold method,treponema pallidum particle agglutination(TPPA),and tolulized red unheated serum test(TRUST),and detection accuracy was explored.Results①Detection rate of TPPA was significantly higher than than TRUST detection method,data difference was significant(P<0.05).②Colloidal gold method had higher detection rate than TRUST,data difference was significant,(P<0.05).③There was no significant difference in detection accuracy between TPPA and colloidal gold detection method,(P>0.05).Conclusion In diagnosis of syphilis,colloidal gold method and treponema pallidum particle agglutination test can detect syphilis actively,which has high detection rate and clinical application value.
作者 张博奇 ZHANG Boqi(Microbial Laboratory Department,Panjin City Disease Control and Prevention Center,Panjin,Liaoning 124010)
出处 《智慧健康》 2024年第21期68-70,共3页 Smart Healthcare
关键词 梅毒诊断 三种梅毒血清学检测方法 对比分析 Syphilis diagnosis Three serological detection methods for syphilis Comparative analysis
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