摘要
目的探讨下肢动脉硬化闭塞症支架内再狭窄患者采用Rotarex机械取栓系统治疗的效果。方法选择2021年2月至2023年2月在郑州大学第一附属医院接受治疗的58例下肢动脉硬化闭塞症支架内再狭窄患者为研究对象,按照随机数字表法分为对照组与观察组,每组29例。对照组采用下肢动脉切开(Fogarty)导管取栓术,观察组采用Rotarex机械取栓术。比较两组血液指标[红细胞计数(RBC)、血红蛋白(Hb)、D-二聚体(D-D)、纤维蛋白原(Fib)]水平、踝肱指数及预后(再通成功例数、复发例数、截肢例数、并发症例数)。结果治疗后,两组D-D、Fib均低于本组治疗前,但两组RBC、Hb、D-D、Fib比较,差异未见统计学意义(P>0.05)。治疗后,两组踝肱指数均高于本组治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。两组再通成功例数比较,差异未见统计学意义(P>0.05),观察组复发例数、截肢例数、并发症发生例数均少于对照组,差异有统计学意义(P<0.05)。结论Rotarex机械取栓系统治疗下肢动脉硬化闭塞症支架内再狭窄能有效改善患者的凝血功能和踝肱指数,降低复发、截肢和并发症的发生风险,保障预后。
Objective To investigate the effect of Rotarex mechanical thrombus extraction system on in-stent restenosis of lower extremity atherosclerotic occlusive disease.Methods A total of 58 patients with intra-stent restenosis of lower extremity arteriosclerosis obliteration treated in the First Affiliated Hospital of Zhengzhou University from February 2021 to February 2023 were selected as the study objects,and were divided into control group and observation group according to random number table method,with 29 cases in each group.The control group was treated with Fogarty catheterization,and the observation group was treated with Rotarex mechanical thrombectomy.The blood indexes[red blood cell count(RBC),hemoglobin(Hb),D-dimer(D-D),fibrinogen(Fib)],ankle-brachial index and prognosis(number of successful recirculation cases,number of recurrence cases,number of amputations,number of complications)of the two groups were compared.Results After treatment,the levels of D-D and Fib in the two groups were lower than those before treatment,but there was no significant difference in RBC,Hb,D-D and Fib between the two groups(P>0.05).After treatment,the ankle-brachial indexes in both groups were higher than those before treatment,and that of the observation group was higher than that of the control group,the difference was significant(P<0.05).There was no significant difference in the number of successful recanalization cases between the two groups(P>0.05),and the number of recurrence cases,amputation cases and complications in the observation group were less than those in the control group,with significant differences(P<0.05).Conclusions The Rotarex mechanical retrieval system for the treatment of in-stent restenosis in lower limb atherosclerotic occlusive disease can effectively improve the patients'coagulation and ankle-brachial index,and reduce their risks of recurrence,amputation,and complications,safeguard their prognosis.
作者
杨雅鸽
李震
秦晶
张楠
靳娅轲
Yang Yage;Li Zhen;Qin Jing;Zhang Nan;Jin Yake(Department of Endovascular Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China;Department of Otology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《临床医学》
CAS
2024年第10期17-20,共4页
Clinical Medicine
关键词
Rotarex机械取栓系统
下肢动脉硬化闭塞症支架内再狭窄
血液指标
踝肱指数
Rotarex mechanical thrombolysis system
In-stent restenosis in lower limb atherosclerotic occlusive disease
Blood indices
Ankle-brachial index
