摘要
目的对347例股骨头坏死患者(ONFH)进行流行病学调查和研究,旨在了解其患病情况和相关影响因素,并为科学防治提供依据。方法采用自行设计的调查表格,回顾性分析2018年1月—2022年12月在某大学附属第一医院和某大学附属第二医院经临床诊断和双髋关节X片、CT、MRI或病理学检查被诊断为ONFH的347例住院患者的病例资料,分析其流行病学特征并对不同类型和不同性别患者进行影响因素分析。结果共纳入347例ONFH患者信息,其中男163例,女184例。ONFH患者年龄19~87岁,平均(61.1±12.4)岁。两种类型ONFH患者年龄、髋关节外伤史、使用激素药物史、CRP、ESR等资料比较差异有统计学意义(P<0.05);不同性别患者在年龄、高血压病史、糖尿病病史、髋关节外伤史、使用激素药物史、ESR、APTT、D-二聚体、FIB、TG方面比较差异均无统计学意义(P>0.05);在BMI、吸烟史、饮酒史、CRP、PT、TC、LDL、HDL方面比较差异有统计学意义(P<0.05)。结论该地区ONFH以NONFH为主要发病类型,女性患者数量要略高于男性患者。不同类型、不同性别患者相比较其影响因素各不相同。
Objective To conduct an epidemiological investigation and study among 347 patients with osteonecrosis of the femoral head(ONFH)to understand the disease status and related influencing factors,and to provide a scientific basis for prevention and treatment.Methods A self-designed questionnaire was used to retrospectively analyze the clinical data of inpatients diagnosed with ONFH by clinical diagnosis and double hip X-ray,CT,MRI,and pathology at the First Affiliated Hospital and the Second Affiliated Hospital of a university from January 2018 to December 2022.The aim was to analyze its epidemiological characteristics and the factors affecting different types of patients and different genders.Results A total of 347 ONFH patients'information was included,with 163 males and 184 females.The average age was(61.1±12.4)years,ranging from 19 to 87 years.Comparison between the two types of ONFH patients showed statistically significant differences in age,history of hip trauma,history of steroid use,C-reactive protein(CRP),and erythrocyte sedimentation rate(ESR)(P<0.05).There were no statistically significant differences in age,history of hypertension,history of diabetes,history of hip trauma,history of steroid use,ESR,activated partial thromboplastin time(APTT),D-dimer,fibrinogen(FlB)and triglyceride(TG)between patients of different genders(P>0.05),while there were statistically significant differences in body mass index(BMI),history of smoking,history of alcohol consumption,CRP,prothrombin(PT),total cholesterol(TC),low-density lipoprotein cholesterol(LDL),and high-density lipoprotein cholesterol(HDL)(P<0.05).Conclusions NONFH is the main type of ONFH in this area,and the number of female patients is slightly higher than that of male patients.The influencing factors were different in different types and sexes of patients.
作者
欧阳玉杰
林莉珍
李嘉琪
王一棋
莫文娟
Ooyang Yujie;Lin Lizhen;Li Jiaqi;Wang Yiqi;Mo Wenjuan(School of Nursing,University of South China,Hengyang,Hunan 421001,China)
出处
《齐齐哈尔医学院学报》
2024年第20期1984-1990,共7页
Journal of Qiqihar Medical University
基金
2023年南华大学护理学院研究生科研创新项目(2023CXKT021)。
关键词
股骨头坏死
危险因素
流行病学
回顾性研究
Osteonecrosis of the femoral head
Risk factors
Epidemiology
Retrospective study
