摘要
目的探究治疗剖宫产产后出血时联用米索前列醇与马来酸麦角新碱的效果。方法非随机选取2018年1月—2022年12月日照市中心医院收治的73例剖宫产产后出血患者为研究对象,按治疗方法的差异进行分组。对照组(n=37)单用米索前列醇,观察组(n=36)联用马来酸麦角新碱。比较两组的产后情况和凝血功能。结果观察组的产后2 h出血量为(198.75±13.44)mL,低于对照组的(142.86±12.25)mL,差异有统计学意义(t=18.182,P<0.05)。相较于对照组,观察组的红细胞计数更高、止血时间更短、输血量更少、住院时间更短和血红蛋白水平更高,差异有统计学意义(P均<0.05)。治疗前两组凝血指标对比,差异无统计学意义(P均>0.05)。治疗后观察组凝血指标均较治疗前改善,且观察组优于对照组,差异有统计学意义(P均<0.05)。结论治疗剖宫产产后出血时联用米索前列醇与马来酸麦角新碱临床效果较好,且凝血指标更优。
Objective To investigate the effect of combining misoprostol with ergonovine maleate in the treatment of postpartum hemorrhage after cesarean delivery.Methods A total of seventy-three patients with postpartum hemor⁃rhage after cesarean section admitted to Rizhao Central Hospital from January 2018 to December 2022 were nonrandomly selected as the research objects,and were divided into groups according to the differences in treatment meth⁃ods.The control group(n=37)received misoprostol alone,and the observation group(n=36)received ergosine maleate in combination.The postpartum condition and coagulation function of the two groups were compared.Results The postpartum 2 h blood loss in the observation group was(198.75±13.44)mL,which was lower than(142.86±12.25)mL in the control group,and the difference was statistically significant(t=18.182,P<0.05).Compared with the control group,the observation group had higher red blood cell count,shorter hemostatic time,less blood transfusion,shorter hospital stay and higher hemoglobin level,and the differences were statistically significant(all P<0.05).Before treat⁃ment,there was no significant difference in coagulation indexes between the two groups(all P>0.05).After treatment,the coagulation indexes of the observation group were improved compared with those before treatment,and the observa⁃tion group was better than the control group,the differences were statistically significant(all P<0.05).Conclusion In the treatment of hemorrhage after cesarean section,the combination of misoprostol and ergotrine maleate has better clinical effect and better coagulation index.
作者
孙士芬
王利平
尹丽娜
SUN Shifen;WANG Liping;YIN Lina(Department of Obstetrics,Rizhao Central Hospital,Rizhao 276800,Shandong,China)
出处
《系统医学》
2024年第20期147-150,共4页
Systems Medicine
