摘要
闪光放疗使用超高剂量率在毫秒时间内将剂量全部注入靶区,其超高剂量率使现有的在线剂量计基本失效,目前通常使用辐射显色胶片来测量剂量。基于中国工程物理研究院应用电子学研究所研制的电子加速器搭建了电子FLASH放疗平台,基于EBT3胶片的快速读出方法,研究了此平台的剂量率范围及剂量分布。实验结果表明,EBT3胶片的快速读出方法可用于电子FLASH放疗的剂量测量,在源皮距100 cm及深度1 cm处剂量率在240~290 Gy/s之间;电子束到达模体表面的平均能量的波动会导致靶区约±5%的剂量波动;面剂量分布满足平坦性在±5%以内和对称性在±3%以内的要求。
FLASH radiotherapy delivers the entire dose to the target area within milliseconds using ultra-high dose rates,rendering existing online dosimeters essentially ineffective.Currently,radiation-sensitive films are commonly employed for dose measurement.Utilizing an electron accelerator developed by the Institute of Applied Electronics of CAEP,an electron FLASH radiotherapy platform was established to investigate the dose rate range and dose distribution using the EBT3 film’s rapid readout method.Experimental results indicate that the rapid readout method of EBT3 films is applicable for dose measurement in electron FLASH radiotherapy,with dose rates ranging from 240 Gy/s to 290 Gy/s at a source-to-skin distance of 100 cm and a depth of 1 cm.Fluctuations in the average energy of the electron beam reaching the surface of the phantom result in dose fluctuations of approximately±5%in the target area.The surface dose distribution meets the requirements of flatness within±5%and symmetry within±3%.
作者
王诗岚
羊奕伟
程德琪
唐镭迅
吴岱
Wang Shilan;Yang Yiwei;Cheng Deqi;Tang Leixun;Wu Dai(Institute of Applied Electronics,CAEP,Mianyang 621900,China;College of Nuclear Science and Technology,Harbin Engineering University,Harbin 150001,China;School of Nuclear Science and Technology,University of South China,Hengyang 421001,China)
出处
《强激光与粒子束》
CAS
CSCD
北大核心
2024年第12期150-156,共7页
High Power Laser and Particle Beams
基金
国家自然科学基金项目(12375318)。
