摘要
目的:探讨临床药师应用用药频度(DDDs)法联合药物利用评估法(DUE)综合评价在外科中成药管理中的应用效果。方法:回顾性分析2022年1月—2022年10月外科患者203例的临床资料作为对照组,由医生或护士提供药物使用指导;2022年11月—2023年8月外科患者的临床资料203例作为观察组,临床药师采取DDDs法联合DUE进行药学干预。对比两组中成药DDDs、日均费用(DDDC)、药物利用指数(DUI)及排序比值、不合理用药情况、药品不良反应发生率。结果:观察组DDDs和DDDC最高的是丹参注射液,瓜蒌皮注射液次之;各中成药的DUI<1,排序比值均≥1;对照组DDDs最高的是注射用血栓通,瓜蒌皮注射液次之;DDDC最高为瓜蒌皮注射液,丹参注射液次之;丹参注射液、注射用血栓通、瓜蒌皮注射液、康莱特注射液的DUI>1;丹参注射液、瓜蒌注射液、康莱特注射液排序比值<1;观察组药物的选择、超医保限药、给药剂量、药物配伍不合理发生率及不良反应发生率低于对照组(P<0.05)。结论:DDDs法联合DUE综合评价中成药的使用,可以加强管理效果,改善DUI与排序比值,促进临床合理用药,减少不良反应。
Objective:To investigate the effectiveness of clinical pharmacists applying the defined daily doses(DDDs)method combined with the drug use evaluation(DUE)comprehensive evaluation in the management of surgical proprietary drugs.Methods:From January 2022 to October 2022,203 cases of surgical patients in our hospital were retrospectively analyzed as control group,and routine pharmaceutical intervention was taken.From November 2022 to August 2023,203 surgical patients in hospital were selected as the observation group,and clinical pharmacists carried out pharmaceutical intervention with DDDs combined with DUE.The DDDs,defined daily dose consumption(DDDC),drug utilization index(DUI)and sorting ratios,irrational use of medication,and the incidence of adverse drug reactions were compared between the two groups.Results:The highest DDDs in observation group was salvia miltiorrhiza injection,followed by Gualsanthis PI injection.The highest DDDC was salvia miltiorrhiza injection,followed by Gualsanthis PI injection.The DUI of all proprietary Chinese medicines was<1,and the ranking ratio was≥1.The highest DDDs in the control group was Xueshuantong for injection,followed by Gualsanpipi injection.The highest DDDC was Gualsanthis PI injection,followed by salvia miltiorrhiza injection.The DUI of salvia miltiorrhiza injection,Xueshuantong injection,Gualsanpi injection and Kanglaite injection was>1;The ordering ratio of salvia miltiorrhiza injection,Salvia Miltiorrhiza injection and Kanglaite injection was<1.The incidence of drug selection,drug exceeding medical insurance limit,drug dose,unreasonable drug compatibility and adverse reaction in observation group were lower than those in control group(P<0.05).Conclusion:DDDs combined with DUE comprehensive evaluation of the use of proprietary Chinese medicines can enhance the management effect,improve the ratio of DUI to sequencing,promote clinical rational drug use,and reduce adverse reactions.
作者
童雪燕
蒋文锋
曾亮平
TONG Xueyan;JIANG Wenfeng;ZENG Liangping(Shangrao Central Hospital,Shangrao 334000,China)
出处
《临床医药实践》
2024年第12期925-928,共4页
Proceeding of Clinical Medicine
基金
上饶市科技计划一般项目(项目编号:2023CZDX82)。
关键词
中成药
临床药师
用药频度
药物利用评估法
不合理用药
proprietary chinese medicine
clinical pharmacist
drug use frequency
drug utilization assessment method
irrational drug use
