摘要
As we navigate the transition from the Fourth to the Fifth Industrial Revolution,the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare.These sectors are benefiting from a synergy of synthetic and engineering biology,sustainable manufacturing,and integrated design principles.Advanced techniques such as 3D bioprinting,tissue engineering,directed assembly,and self-assembly are instrumental in creating biomimetic scaffolds,tissues,organoids,medical devices,and biohybrid systems.The field of biofabrication in the United Kingdom and Ireland is emerging as a pivotal force in bioscience and healthcare,propelled by cutting-edge research and development.Concentrating on the production of biologically functional products for use in drug delivery,in vitro models,and tissue engineering,research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability,affordability,and healthcare system benefits.
基金
supported by the W.D.Armstrong Trust.YYSH is funded by the European Research Council(ERC-St G,758865)
the UK Research and Innovations(UKRI)Biotechnology and Biological Sciences Research Council(BB/W014564/1)
funding from a UKRI Future Leaders Fellowship(MR/V024965/1)
supported by the BBSRC London Interdisciplinary Doctoral(LIDo)Programme
the funding support of EPSRC(EP/W004860/1,EP/X033686/1)and MRC(MR/V029827/1,MR/W030381/1)
the European Research Council(Pro Li Cell,772462)for support
the NIHR Nottingham Biomedical Research Centre,University of Nottingham,Nottingham,UK and the AO Foundation,AO CMF(AOCMF-21-04S)
funding support from grant MR/W01470X/1
the EPSRC(EP/W018977/1)for financial support
funding from the EPSRC(EP/T020792/1)
funding from Biomat DB+(Horizon Europe 101058779)
funding received from Science Foundation Ireland(SFI)—Grant No.13/RC/2073_P2。
