摘要
目的掌握重庆口岸出国移民人员活动性肺结核流行现状。方法选取2014—2018年重庆市健康之友国际诊所赴英国及澳大利亚移民体检者中X线胸片异常者,对痰涂片镜检、痰培养及药敏试验结果进行回顾性分析。结果共筛查出176名胸片异常者,男性48.9%,女性51.1%。176名患者涂片镜检均未发现抗酸杆菌,有38例MGIT 960培养阳性,阳性率为21.6%,其中20例为肺结核,18例为非结核分枝杆菌感染;男性较多,主要集中于30岁以下和60岁以上。14例完成药敏检测的病例中,有7例为耐药结核,其中4例为耐多药结核;5种抗结核药物中,利福平的耐药率最高,最低为乙胺丁醇。结论重庆口岸出国移民中菌阳活动性肺结核以涂阴培阳患者为主,耐药率高。今后应加强对胸片异常者的结核分枝杆菌培养。
Objective To understand the prevalence of active pulmonary tuberculosis(PTB)among immigrate applicants in Chongqing port.Methods The cases of immigrants to Britain and Australia with abnormal chest X-ray screening in Chongqing Healthmate International Clinic from 2014 to 2018 were selected as subjects.The results of sputum smear,sputum culture and drug-susceptibility test of these cases were analyzed.Results A total of 176 cases with abnormal chest X-ray were screened.Among them,the males accounted for 48.9%and the females accounted for 51.1%.No smear-positive case was found.There were 38 cases showed cultured positive with MGIT960,the positive rate was 21.6%.Among the 38 cases,20 cases were identified as PTB and 18 cases were identified as non-tuberculosis mycobacterium.The male cases were more than those of the females among the PTB pa-tients,most of the cases were below 30 years or above 60 years old.The drug-susceptibility test was conducted in14 cases,7 of them were drug-resistant tuberculosis and 4 were multidrug-resistant tuberculosis.Among the 5 antituberculosis drugs,rifampicin had the highest drug-resistant rate,and the lowest one was ethambutol.Conclusion The sputum-positive active PTB patients in Chongqing port were mostly smear-negative and culture-positive,with higher drug resistance rate.In the future,we should to strengthen the Mycobacterium tuberculosis culture for the persons with abnormal chest X-ray.
作者
熊敏
罗明
张汇征
杨晶
陈耀凯
李俊刚
王静
李同心
周刚
李桓
XIONG Min;LUO Ming;ZHANG Hui-zheng;YANG Jing;CHEN Yao-kai;LI Jun-gang;WANG Jing;LI Tong-xin;ZHOU Gang;LI Huan(Chongqing Public Health Medical Center,Chongqing 400036,China)
出处
《中国国境卫生检疫杂志》
CAS
2019年第2期129-132,共4页
Chinese Journal of Frontier Health and Quarantine
基金
中国科学院高致病性病原生物学与生物安全重点实验室开放研究基金资助项目(2017SPCAS004)
重庆市卫生与计划生育委员会科研项目(2017MSXM115)
关键词
肺结核
移民
痰培养
耐药性
Pulmonary tuberculosis
Immigration
Sputum culture
Drug-resistance
