摘要
目的探讨冠状动脉粥样硬化性心脏病(以下简称冠心病)患者血液脂蛋白相关磷脂酶A2(Lp-PLA2)、超敏C反应蛋白(hs-CRP)及D-二聚体检测的相关性。方法选择260例冠心病患者作为观察组,260例健康体检者作为对照组,检测两组研究对象血清Lp-PLA2、hs-CRP、D-二聚体及各项生化指标水平,采用Spearman相关性分析检验各项检测指标的关系。结果观察组患者Lp-PLA2、hs-CRP、D-二聚体水平明显高于对照组,且Lp-PLA2、hs-CRP及D-二聚体与心功能指标均呈正相关(r=0.873、0.782、0.674,P<0.05)。结论 Lp-PLA2、hs-CRP及D-二聚体检测是诊断冠心病的重要指标。
Objective To study the correlations among the lipoprotein associated phospholipase A2(Lp-PLA2),hypersensitive C-reactive protein(hs-CRP)and D-dimmer in patients with the coronary heart disease.Methods 260 cases of patients with coronary heart disease(CHD)were enrolled in the study as observation group and 260 healthy people from the physical examinations were recruited as control group.The concentrations of Lp-PLA2,hs-CRP,D-dimer and other biochemical indicators in blood sera of the two groups were detected,using the Spearman correlation analysis to test the relationship between those indicators.Results The Lp-PLA2,hs-CRP,D-dimer levels of the observation group were obviously higher than those of control group.The Lp-PLA2 level of the observation group was positively correlated with the cardiac function index(r=0.873,P<0.05).hs-CRP was positively correlated with cardiac function index(r=0.782,P<0.05).D-dimmer was positively correlated with the functional grades of heart(r=0.674,P<0.05).Conclusion Lp-PLA2,hs-CRP and D-dimer could be important indicators for the detection of coronary heart disease.
出处
《国际检验医学杂志》
CAS
2016年第2期164-165,168,共3页
International Journal of Laboratory Medicine
