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硒对大骨节病区儿童肾脏磷代谢的影响

Renal Phosphorus Metablism and Its Relationship with Selenium in Children from Kashin-BeckDisease Affected Areas
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摘要 本文通过测定大骨节病区、服硒病区及非病区儿童的血、尿磷及尿硒含量,计算了磷廓清率、尿磷排泄率、肾小球滤过磷、肾小管重吸收磷及重吸收百分率。结果表明:尿硒病区组低于其他两组;血、尿磷及尿硒排泄率病区组显著低于服硒病区组;尽管三组间滤过磷及重吸收磷百分比无显著性差异,但服硒病区组滤过磷较其他两组呈增高,重吸收磷百分率呈降低趋势。这些说明硒对病区儿童磷代谢有明显影响。 Phosphorus (P) contents of plasma and urine as well as urinary Se were determined and renal plasma P clearance (Cp), P excretion rate(Ep), P glomerular filtration rate (Fp) and P tubular reabsorption ratio (Ap) were calculated based on above data in children from an en-demic area, a Se-fortified endemic area and a non-endemic area. Results showed that urinary Se of endemic children was the lowest in the three groups, Ep in Se-fortified endemic children increased contrasted with the other two groups, and that there were not significant differences in other parameters above mentioned among the three groups but there existed tendencies to incerease in Fp and decrease in Ap of Se-fortified endemic children, those indicated that there was significant effect of Se on the P metabolism of endemic children.
出处 《地方病通报》 1992年第2期69-72,共4页 Endemic Diseases Bulletin
关键词 大骨节病 肾脏 磷代谢 儿童 Kashin-beck disease Renal P metabolism Se Children
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参考文献3

  • 1蒋一方,白偲,于志道,李永莉,许援朝,王惠芬,莫晓燕.低硒儿童的肌肉代谢[J]西安交通大学学报(医学版),1986(02).
  • 2杨建伯.大骨节病区儿童血清磷、钙水平与钙磷比值的研究[J]中国地方病学杂志,1986(01).
  • 3王光亚,周瑞华,孙淑庄,殷太安,刘胜杰,杨光圻.生物样品、水及土壤中痕量硒的荧光测定法 一、发、血、尿和其它组织中痕量硒的测定[J]营养学报,1985(01).

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