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氯胺酮复合羟丁酸钠麻醉在小儿烧伤整形手术中的临床应用研究 被引量:1

Application of Ketamine Combined With Sodium Gamma Hydroxybutylate During Burn and Orthopedic Operation of Children
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摘要 目的 :观察氯胺酮及羟丁酸钠在小儿烧伤整形手术中的临床麻醉效果。方法 :选择 12 8例行四肢及躯干部位烧伤整形手术患儿 ,年龄 0 8~ 6(3± 2 3)岁 ,体重 6~ 2 0 (11± 6)kg ,以氯胺酮 4~ 6mg/kg肌注行基础麻醉 ,术中间断推注氯胺酮和羟丁酸钠维持麻醉 ,记录 12例大面积烧伤的血常规、电解质、术前术后血气 ,术中监测心率、血压、SpO2 。结果 :12例大面积烧伤患儿术前术后血气、血常规、电解质无显著差异(P >0 0 5 ) ,心率增减在 2 0次 /min之内占 4 1 3% ,增快大于 2 0次 /min ,占 5 1 9% ;呼吸频率变化小于 5次 /min ,占 62 5 % ,增快大于 5次 /min ,占 2 3 1%。SpO2 为 96 3± 1 5 %。结论 Objective:To investigate the effects of ketamine combined with sodium gamma hydroxybytylate on burn or orthopedic operation on the extremities or trunks.Method:The cases with burn or orth opedic on the extremities of trunks were selected and all of them were aged 0.8~6 years old and weighed 6~20kg.The basic anesthesia was performed with first dose of ketamine in 4~6mg/kg,then the push dose of ketamine combined with sodium gamma hydroxybytylate was given internmittently to maintain anesthsia during operation.The blood routine,electrolytes,pre-and post-operative blood-gas in 12 cases of large area burn were recorded and heart rate,blood presure and SPO 2 were aslo monitored during operation.Results:No statistically differences were obtained in such indexes as blood routine,electrolytes,pre-and postoperative blood-gas in 12 cases of large area burn (P>0 05).The incidence of heart rate change within and over 20/min was 41.3% and 51.9% respectively;The incidence of BP change within and over 5/min was 62.5% and 23.1% respectively;The SpO 2 was in the range of 96.3±1.5%.Conclusions:It is safe and practical to perform anesthesia by intraveous ketamine combined with gamma hydroxybutylate in burn and orthopedic operation on extremities and trunk.
作者 艾国 王建景
出处 《内蒙古医学杂志》 2002年第6期494-495,共2页 Inner Mongolia Medical Journal
关键词 氯胺酮 羟丁酸钠 麻醉 小儿 烧伤 整形手术 临床应用 Ketamine Sodium gamma hydroxygutylate Children Burn Orthopedic
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