摘要
目的探讨铝碳酸镁对胆汁返流性胃炎的疗效。方法64例胆汁返流性胃炎,随机分为2组。对照组(n=30)服多潘立酮,治疗组(n=34)同时服铝碳酸镁和多潘立酮。治疗4周后观察腹痛、腹胀、呕吐胆汁等症状变化,以及胃镜下胃粘膜炎症变化。结果治疗后2组患者症状均明显减轻(P<0.01),对照组和治疗组的症状有效率分别为76.7%,94.1%(P<0.01),胃镜下胃粘膜炎症好转总有效率分别为66.7%,91.2%(P<0.01),均无明显不良反应发生。结论铝碳酸镁可结合胃内胆汁,有效缓解胆汁返流性胃炎症状及胃镜下胃粘膜炎症,不良反应少,为治疗胆汁返流性胃炎的有效药物,值得临床推广。
Objective To investigate the efficacy of hydrotalcite in the treatment of bile reflux gastritis.Methods 64 cases of bile reflux gastritis were randomly divided into the control group treated with domperidone and the treatment group managed with hydrotalcid and domperidone.After 4 weeks treatment,abdominal pain,abdominal distension,vomiting and other symptoms of biliary changes,and changes in endoscopic gastric mucosal inflammation were evaluated.Results After the treatment,the symptoms of patients in 2 groups were significantly alleviated(P<0.01),and the rate of symptoms alleviation and endoscopic mucosal inflammation improvement were 76.7%,66.7% and 94.1%,91.2% in the control group and the reatment group respectively(P<0.01).There were no significant adverse events.Conclusion Hydrotalcite combined with domperidone can treat bile reflux gastritis effectively,with less adverse reactions,which is worthy to be popularized.
出处
《海南医学》
CAS
2009年第S5期179-181,共3页
Hainan Medical Journal
