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姜黄素抗肿瘤机制的研究进展 被引量:4

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摘要 姜黄素具有抗氧化、抗炎、抗凝、降血脂、抗动脉粥样硬化等主要作用,而其主要的抗癌作用现已被广泛的研究,主要从调控肿瘤细胞周期、诱导肿瘤凋亡、抑制侵袭、转移和逆转肿瘤耐药并提高肿瘤对化疗的敏感性等几方面起作用。并且其毒副作用小,安全性高,俨然成为具有治疗前景的抗癌药物。
出处 《海南医学》 CAS 2016年第17期2828-2831,共4页 Hainan Medical Journal
关键词 姜黄素 肿瘤 综述
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参考文献30

  • 1Ying-Ying Xu,Yang-Yang Bao,Shui-Hong Zhou,Jun Fan.??Effect on the Expression of MMP-2, MT-MMP in Laryngeal Carcinoma Hep-2 Cell Line by Antisense Glucose Transporter-1(J)Archives of Medical Research . 2012 (5)
  • 2蒋金,曹友德,磨娜,李静,莫显刚.姜黄素通过P53/P21/PCNA/eIF4E信号通路抑制A549细胞增殖[J].第三军医大学学报,2012,34(1):49-53. 被引量:13
  • 3Zhigang Fan,Xiaoyi Duan,Hui Cai,Li Wang,Min Li,Jingkun Qu,Wanjun Li,Yongheng Wang,Jiansheng Wang.??Curcumin inhibits the invasion of lung cancer cells by modulating thePKCα/Nox-2/ROS/ATF-2/MMP-9 signaling pathway(J)Oncology Reports . 2015 (2)
  • 4Hai Jin,Fan Qiao,Yan Wang,Yongdong Xu,Yan Shang.??Curcumin inhibits cell proliferation and induces apoptosis of humannon-small cell lung cancer cells through the upregulation of miR-192-5p and suppressionof PI3K/Akt signaling pathway(J)Oncology Reports . 2015 (5)
  • 5金子,蔡颖,张晔,刘云鹏,曲秀娟,徐玲,侯科佐.姜黄素对人结肠癌细胞PI3-K/Akt和MEK/ERK信号通路的影响[J].现代肿瘤医学,2015,23(12):1629-1631. 被引量:16
  • 6Yuqi Sun,Jie Zhang,Jiaying Zhou,Ziyuan Huang,Haiyang Hu,Mingxi Qiao,Xiuli Zhao,Dawei Chen.??Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug resistance in human hepatoma cells(J)European Journal of Pharmacology . 2015
  • 7Mingxiang Ye,Jin Zhang,Ji?n Zhang,Qing Miao,Libo Yao,Jian Zhang.??Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer(J)Cancer Letters . 2014
  • 8徐炜,陈清勇.Rho GTP酶在姜黄素抑制人肺癌细胞增殖和转移中的作用[J].中国现代应用药学,2013,30(5):475-480. 被引量:5
  • 9Abo Bakr Abdel Shakor,Mona Atia,Ismail Ahmed Ismail,Ali Alshehri,Hesham El-Refaey,Katarzyna Kwiatkowska,Andrzej Sobota.??Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation(J)BBA - Molecular and Cell Biology of Lipids . 2014
  • 10Qing-yong Chen,Ying Zheng,De-min Jiao,Fang-yuan Chen,Hui-zhen Hu,Yu-quan Wu,Jia Song,Jie Yan,Li-jun Wu,Gui-yuan Lv.Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway[J]. The Journal of Nutritional Biochemistry . 2013

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