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TPO基因及其应用研究

The research and application of TPO's gene
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摘要 TPO甲状腺过氧化物酶是甲状腺细胞膜上的一种糖蛋白,是合成甲状腺激素的关键酶。深入研究其基因结构及转录调控对甲状腺疾病和放射性碘治疗具有重要意义。 Thyroperoxidase (TPO)is a glycosylated protein bound to the apical plasma membrane of thyrocytes.It is the key enzyme in the synthesis of thyroid hormones.Its gene structure and transcriptional regulation have been deeply studied.This article reviews the development of TPO's gene structure,function,transcriptional regulation,the relation-ship between TPO with thyroid diseases and radioactive iodide therapy.
作者 邢岩
机构地区 四川大学华西医院核医学科
出处 《国外医学（放射医学核医学分册）》 2002年第6期248-252,共5页 Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
基金 国家自然科学基金资助项目(30170281)
关键词 甲状腺过氧化物酶 放射性碘治疗 甲状腺疾病 基因结构 基因转录调控 thyroid peroxidase radioactive iodide therapy
分类号 R730.5 [医药卫生—肿瘤]
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参考文献23

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国外医学（放射医学核医学分册）
2002年 第6期

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