摘要
目的分析重度颈动脉狭窄颅内侧支循环代偿状态与缺血性脑卒中(IS)的相关性。方法选取100例合并重度颈动脉狭窄的IS患者为研究对象,对其前交通动脉(ACOA)开放、后交通动脉(PCOA)开放、眼动脉(OA)开放等侧支循环情况、治疗前和治疗2周时美国国立卫生研究院卒中量表(NIHSS)评分、入院时和发病6个月时改良Rankin评分(mRS)进行观察和比较。结果治疗2周时,单纯ACOA开放、单纯POCA开放和多支侧支循环开放患者的NIHSS评分均较治疗前显著下降(t=4.328、4.226、6.133,P<0.05),其中,多支侧支循环开放的患者NIHSS评分最低,其次为单纯ACOA开放或单纯POCA开放的患者,而单纯OA开放或无侧支循环开放患者最高,差异均有统计学意义(q=3.237~5.636,P<0.05);发病6个月时,单纯ACOA开放、单纯POCA开放和多支侧支循环开放的患者mRS评分均较治疗前显著下降(t=3.244、3.057、3.675,P<0.05),其中,多支侧支循环开放、单纯ACOA开放或单纯POCA开放的患者mRS评分显著低于单纯OA开放或无侧支循环开放的患者(q=2.987~3.732,P<0.05)。结论多重侧支循环或颅内主要动脉侧支循环的建立可显著降低IS患者的神经功能损害程度,改善患者近期预后,利于康复。
Objective To analyze the relationship between the compensatory state of intracranial collateral circulation of severe carotid artery stenosis and ischemic stroke(IS).Methods One hundred IS Patients complicated with severe carotid artery stenosis were selected as the research objects.The collateral circulation status of anterior communicating artery(ACOA)opening,posterior communicating artery(PCOA)opening,the ophthalmic artery(OA)opening,the National Institutes of Health Stroke Scale(NIHSS)scores before the treatment and in the 2nd week after the treatment,the modified Rankin score(mRS)on admission and in the 6th month after onset of IS were observed and compared.Results In the 2nd week after the treatment,the NIHSS scores of the patients with single ACOA opening,single POCA opening and multiple collateral circulation opening were significantly lower than those before the treatment(t=4.328,4.226,6.133,P<0.05),in which the patients with multiple collateral circulation opening got the lowest the NIHSS scores,followed by the patients with single ACOA opening or single POCA opening,and the patients with single OA opening or without collateral circulation hold the highest NIHSS scores,the differences were all statistically significant(q=3.237~5.636,P<0.05);In the 6th month after onset,the mRS scores of the patients with single ACOA opening,single POCA opening and multiple collateral circulation opening were significantly lower than those before the treatment(t=3.244,3.057,3.675.P<0.05),in which,the mRS scores of the patients with single ACOA opening,single POCA opening or multiple collateral circulation opening were significantly lower than that of the patients with single OA opening or without collateral circulation(q=2.987~3.732,P<0.05).Conclusion The establishment of multiple collateral circulation or collateral circulation of major intracranial artery can significantly reduce the degree of neural function damage of IS patients and can improve the prognosis of IS patients,which is conducive to the rehabilitation of patients.
出处
《中国实用神经疾病杂志》
2016年第9期6-8,共3页
Chinese Journal of Practical Nervous Diseases
关键词
重度颈动脉狭窄
侧支循环
缺血性脑卒中
Severe carotid artery stenosis
Collateral circulation
Ischemic stroke
