摘要
目的 :探究产妇在分娩过程中应用催产素及不同剂量的催产素对新生儿高胆红素血症的影响,为临床提供指导意见。方法 :选取来我院出生的足月健康新生儿339例作为研究对象,按照分娩过程中是否使用催产素分为两组,未使用催产素的223例新生儿作为对照组,使用催产素的116例新生儿作为观察组,全部新生儿出生后第3、5、7天检测新生儿胆红素变化情况,在出生7d后记录新生儿高胆红素血症及窒息发生率。结果 :对照组出生后血胆红素值存在显著差异,与出生后3d比,出生后5d无差异,出生后7d显著降低,观察组出生后血胆红素值存在显著差异,与出生后3d比,出生后5d存在显著差异,出生后7d显著降低,两组间在出生后3d、5d、7d血胆红素值存在显著差异;在出生后3d,不同剂量催产素组间血胆红素值存在差异,5IU组和10IU组显著高于1.5IU组和2.5IU组,在出生后5d和7d,不同剂量催产素组间血胆红素值存在差异,随着剂量增加,血胆红素值显著升高;在高胆红素血症发生率上,对照组新生儿为21.97%(49/223),观察组新生儿为37.93%(44/116),存在显著差异;在窒息发生率上,对照组新生儿为4.04%(9/223),观察组新生儿为14.66%(17/116),存在显著差异。结论 :孕妇分娩时使用催产素可是新生儿高胆红素血症的高危因素,剂量越大,血胆红素升高越明显。
Objective to explore the application of oxytocin during labor and maternal high different dose of oxytocin on neonatal bilirubin hematic disease, provide guidance for clinical. Methods to select 339 full-term healthy newborns born to our hospital patients as the research object, according to whether or not to use in the process of childbirth oxytocin is divided into two groups, 223 cases of patients who did not use the oxytocin neonatal as control group, and use of oxytocin, 116 cases of neonatal as observation group, and all 3, 5, and 7 days after birth detect neonatal bilirubin, was born in 7 d after record high neonatal bilirubin levels and the incidence of asphyxia. Results in the control group after the birth of blood bilirubin value ex-ists significant difference, and after the birth of 3 d, 5 d after birth no difference, after the birth of the 7 d significantly reduced, the observation group after the birth of blood bilirubin value exists significant difference, and after the birth of 3 d, 5 d after birth there is significant difference, after the birth of the 7 d significantly reduced, between the two groups in 3 d, 5 d, 7 d after birth blood bilirubin value exists significant difference; In 3 d after birth, the different dose of oxytocin blood bilirubin value differ-ences between groups, 5 IU group and 10 IU group is significantly higher than 1.5 IU group and 2.5 IU group, 5 d and 7 d after birth, blood bilirubin values between different dose of oxytocin group differences, with the increase of dosage, blood bilirubin values significantly increased; Newborn on the incidence of high blood bilirubin, control group was 21.97% (49/223), the ob-servation group of newborns was 37.93% (44/116), there were significant differences; Newborn on the incidence of asphyxia, control group was 4.04% (9/223), the observation group of newborns was 14.66% (17/116), there were significant differences.Conclusion pregnant women in childbirth using oxytocin but high neonatal bilirubin levels, risk factors, the greater the dose, elevated blood bilirubin, the more obvious.
出处
《湖南师范大学学报（医学版）》
2016年第1期59-61,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
催产素
新生儿
高胆红素血症
窒息
oxytocin
The newborn
High blood bilirubin
choking
