摘要
目的:通过特异性IgE(sIgE)检测分析荨麻疹患者过敏原的分布特点。方法:采用ELISA法对1 355例荨麻疹患者进行血清过敏原sIgE检测。结果:1 355例荨麻疹患者过敏原sIgE阳性检出率为69. 0%(935例),sIgE阳性检出率较高的吸入性过敏原主要为霉菌(21. 5%)、螨(17. 4%)和梧桐花粉(14. 2%),食物性过敏原主要为鸡蛋(23. 5%)和花生(13. 1%)。男性患者总IgE增高者检出率高于女性(P <0. 001)。13～18岁年龄段人群sIgE检出率达到峰值。结论:荨麻疹患者过敏原以霉菌、鸡蛋、尘螨为主,过敏情况存在性别、年龄差异。
Aim: To explore the prevalence of serum allergen-specific IgE in patients with urticaria. Methods: The serum allergen-specific IgE of 1 355 patients with urticaria was detected by ELISA. Results: The positive rate of allergen-specific IgE in 1 355 patients was 69. 0%;the most common inhale allergens were mold( 21. 5%) ,mites( 17. 4%) and phoenix tree pollen( 14. 2%);while the corresponding ingested allergens were eggs ( 23. 5%) and peanuts( 13. 1%) . The positive rate of total IgE in male patients was higher than that in females( P < 0. 001) . The positive rate of total IgE got to the peak stage in the patients aged 13 - 18 years. Conclusion: The main allergens of urticaria patients are mold,eggs and mites,and the status of the patients varied by sex and age.
作者
平杰丹
赵俊伟
孙晓旭
吴凡
王央霞
马小涵
明亮
PING Jiedan;ZHAO Junwei;SUN Xiaoxu,WU Fan;WANG Yangxia;MA Xiaohan;MING Liang(Department of Clinical Laboratory,the First Affiliated Hospital,Zhengzhou University,Zhengzhou450052;Key Clinical Laboratory of Henan Province,Zhengzhou 450052)
出处
《郑州大学学报（医学版）》
CAS
北大核心
2018年第6期788-791,共4页
Journal of Zhengzhou University(Medical Sciences)
基金
国家自然科学基金资助项目(81501715)
