摘要
白细胞介素-33与其受体ST2L结合可促进Th2方向的免疫炎症反应,白细胞介素-33/ST2L通路调节免疫反应与多种疾病的发生与进展有关,研究白细胞介素-33/ST2L通路与心血管系统疾病、哮喘等变态反应性疾病、自身免疫性疾病、皮肤系统性疾病及纤维化相关疾病等的关系可为疾病的治疗提供新思路和新方法。本文就白细胞介素-33/ST2L通路与疾病相关性的研究进展作一综述。
Interleukin-33(IL-33)could promote Th2 immune inflammatory response by combining its receptor ST2 L.IL-33/ST2 Lpathways regulate immune response,which is associated with the development and progress of many diseases.The research on the correlations of IL-33/ST2 Lpathways with cardiovascular system diseases,asthma and allergic diseases,autoimmune diseases,skin diseases and fibrosis could provide a new thought and method for their therapy.This paper reviews the research progress of the correlations between IL-33/ST2 Lpathways and diseases.
出处
《中华实用诊断与治疗杂志》
2017年第6期616-618,共3页
Journal of Chinese Practical Diagnosis and Therapy
基金
国家自然科学基金(81400713)
黑龙江省自然科学基金(H201337)
