摘要
利用能量匹配原则将无机半导体ZnO纳米粒子与有机半导体四苯基卟啉四羧酸(TCPP)分子进行组装,在无机-有机组分之间的界面构建了杂化纳米分子口袋ZNPs-TCPP,该纳米分子口袋对四苯基卟啉(TPP)分子具有高选择性识别功能,同时其荧光增强了5倍以上,并成功地将该杂化纳米分子口袋用于肺腺癌细胞(A549)的细胞成像.
An inorganic/organic hybrid nanoscale molecular pocket ZNPs-TCPP was constructed through the assembly of 5,10,15,20-tetra(3-carboxyphenyl) porphyrin(TCPP) on the surface of ZnO nanoparticles(NPs), which highly selectively recognized 5,10,15,20-tetraphenylporphyrin(TPP) molecule. The resulting hybrid nanoscale molecular pockets ZNPs-TCPP captured TPP demonstrated high emission efficiency and the intensity of its emission was five times greater than that of ZnONPs-TCPP. Significantly, the molecular pocket ZNPs-TCPP-TPP with high luminescence can be dispersed in water and is successfully applied for the cell imaging of A549.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
2014年第12期1218-1222,共5页
Acta Chimica Sinica
基金
国家自然科学基金(Nos.21373235,21031006)
国家重点基础研究计划(Nos.2011CB932302,2011CB932303)资助~~
关键词
纳米分子口袋
卟啉
无机/有机杂化
细胞成像
nanoscale molecular pockets
porphyrin
inorganic/organic hybrid
cell imaging
