摘要
[目的]探讨影响喉癌生存率的因素以及病理学切缘在上述诸多因素中的地位。[方法]回顾性分析253例喉癌临床资料 ,比较喉癌切缘阴阳性患者的生存率 ,Cox回归模型分析影响喉癌预后的诸因素。[结果]①病理学切缘阳性率是20.2% (51/253) ,相对阴性切缘而言 ,切缘阳性者的生存率低 (37.52 %vs64.37% ,P<0.05)。②单因素分析时年龄、肿瘤生长部位、病理学类型、临床分期、淋巴结有无转移、切缘阴阳性和手术方式均有统计学意义 (P值均<0.05) ;但多因素分析时只有年龄、临床分期、淋巴结有无转移、切缘阴阳性才有意义(P均<0.05)。[结论]切缘阳性者的生存率较阴性者差 ,病理学切缘和淋巴结、临床分期一样都是影响喉癌预后的重要因素。
To investigate the factors affecting the survival rate of laryngeal carcinoma and the value of pathological positive margin among the factors.Two hundred and fifty three cases were analyzed retrospectively.The survival rate between the positive and negative margin was compared.The Cox model was used to analyze the factors.①The rate of pathological positive margin was 20.2%(51/253); The survival rate of positive margin was lower than that of negative(37.52% vs 64.37%,P<0.05).② The age, primary site, pathological type, clinical stage, lymph node status, margin and operation type were proven to significant when univariate analysis (P<0.05); but multivariate analysis showed that only the age, clinical stage, lymph node status and pathological margin were significant (P<0.05).[Conclusions]The survival rate in patients with pathologically positive margin is worse than those with negative margin.Clinical stage and lymph node status, pathological positive margin are important factors affecting the survival rate of laryngeal carcinoma too.
出处
《中国肿瘤》
CAS
2002年第11期655-657,共3页
China Cancer
关键词
癌
鳞状细胞
喉肿瘤
生存率
切缘
影响因素
carcinoma,squamous cell
laryngeal neoplasms
survival rate
margin
impact factor
