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HIV/AIDS与口腔白色念珠菌病 被引量:22

Oral Candidiasis in HIV/AIDS Patients
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摘要 目的 :研究白色念珠菌病 (白念病 )在艾滋病 (AIDS)中的发病机制和临床表现 ,提高临床医师对该病的警惕性。方法 :对 2 0例HIV AIDS患者进行系统体检 ,重点观察口腔病损情况 ,并行刮片检查和真菌培养。结果 :全身症状主要为间断咳嗽、长期腹泻、低热、肝脾肿大、进行性体重减轻。 18例发生严重的口腔白念病 ,1例伴消化道白念菌感染。结论 :HIV感染导致免疫功能低下 ,易引起真菌、细菌、病毒等机会性感染 ,口腔白念病常被认为是HIV感染的先兆症状 ,也易合并或继发于其它病损 (如毛状白斑、卡波济肉瘤及口腔溃疡 ) ,对其早期诊治 ,可防止感染向口咽、食道。 Objective: To study the candidiasis function in HIV infected patients is benefit for diagnosis. Methods: The participants were 20 HIV postive or AIDS patients. Oral health evaluation was performed and oral fungal culture was taken. Results: Clinic symptoms included:cough, diarrhea, fever, weigh loss. There were 18 patients with severe oral candidiasis. There was one case with severe candidiasis in digestion system. Conclusion: Due to immunosuppression in HIV/AIDS patients, fungal, bacterial and virus infection developed frequently. Candidiasis albicans was found in HIV infected patients as first sign. It is secondary complication to other lesions(hair leukoplakia, Kaposis's sacoma and oral ulcer). Early diagnosis and treatmeat are important to prevent oropharyngeal candidiasis.
出处 《武汉大学学报(医学版)》 CAS 2003年第1期83-85,共3页 Medical Journal of Wuhan University
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