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内分泌疾病的基因治疗研究进展

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摘要 内分泌疾病领域中应用基因治疗的思路主要有 :转基因治疗激素单一缺乏的垂体性尿崩症、生长激素缺乏症和 2 1羟化酶缺乏症等 ;基因转导调节机体免疫状态治疗自身免疫性甲状腺炎和 1型糖尿病等 ;转导增强免疫、杀灭或抑制肿瘤的基因 ,治疗垂体、甲状腺。
出处 《国外医学(内分泌学分册)》 2003年第1期12-14,共3页 Foreign Medical Sciences(Section of Endocrinology)
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  • 1Geddes B J;Harding T C;Lightman S L.Long-term gene therapy in the CNS: reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin[J],1997.
  • 2Lee E J;Duan W R;Kotlar T.Restoration of growth hormone-releasing hormone (GHRH) responsiveness in pituitary GH3 cells by adenovirus-directed expression of the human GHRH receptor[J],2001(142).
  • 3Windeatt S;Southgate T D;Dewey R A.Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas[C],2000.
  • 4Batteux F;Trebeden H;Charreire J.Curative treatment of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for interleukin-10[J],1999.
  • 5Batteux F;Lores P;Bucchini D.Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis,2000.
  • 6Nagayama Y;Shigematsu K;Namba H.Inhibition of angiogenesis and tumorigenesis,and induction of dormancy by p53 in a p53-null thyroid carcinoma cell line in vivo,2000.
  • 7Kim S B;Ahn I M;Park H J.Growth inhibition and chemosensitivity of poorly differentiated human thyroid cancer cell line (NPA) transfected with p53 gene[J],2001(23).
  • 8Zhang R;Straus FH;DeGroot LJ.Adenoviral-mediated gene therapy for thyroid carcinoma using thymidine kinase controlled by thyroglobulin promoter demonstrates high specificity and low toxicity[J],2001(2).
  • 9Spitzweg C;Harrington K J;Pinke L A.Clinical review 132: The sodium iodide symporter and its potential role in cancer therapy,2001.
  • 10Lundberg C;Jungles S J;Mulligan R C.Direct delivery of leptin to the hypothalamus using recombinant adeno-associated virus vectors results in increased therapeutic efficacy[J],2001.

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