摘要
为研究腺嘌呤制作 SD大鼠肾阳虚型慢性肾功能衰竭模型的生物化学改变 ,以腺嘌呤 2 0 0 mg/kg· d灌服 SD大鼠制作肾阳虚型慢性肾功能衰竭模型 ,取血样作肾脏病常用生化指标检测 ,结果符合慢性肾功能衰竭主要生化改变 ,说明以腺嘌呤制作 SD大鼠肾阳虚型慢性肾功能衰竭模型在生化研究方面达到较理想的结果 ,其临床症状符合中医肾阳虚型动物模型表现 ,是可供科研。
To study the biochemical changes of models of kidney YANG deficiency replicated by adenine in SD rats of chronic renal failure,the models of SD rats were replicated by taking 200 mg/kg.d adenine,and then the common chemical indexes of renal diseases were examined.The results accorded with the mainly chemical changes of chronic renal failure.It indicates that the models are satisfactory in biochemical study,and its clinical symptoms accord with TCM kidney YANG deficiency.The models may be use in research and teaching work.\;
出处
《福建中医学院学报》
2003年第1期22-24,共3页
Journal of Fujian College of Traditional Chinese Medicine
基金
福建省自然科学基金资助课题 (C970 5 0 )
关键词
腺嘌呤
肾阳虚
慢性肾功能衰竭
动物模型
生化研究
adenine
kidney YANG deficiency
chronic renal dysfunction
animal model
chemical study
