摘要
目的 观察经皮椎体成形术 (PVP)、PVP和血管内栓塞化疗术综合治疗椎体恶性肿瘤的疗效。方法 2 9例患者 (男性 16例 ,女性 13例 )共 4 0个椎体 ,转移性肿瘤 2 8例 ,多发性骨髓瘤 1例 ,均表现为胸腰部疼痛 ,2例有不同程度的脊髓功能障碍。 18例患者共 2 6个椎体单独行PVP治疗 ,11例16个椎体先后行PVP和 (或 )血管内栓塞化疗术。结果 2 9例患者经PVP和血管内栓塞化疗后症状完全缓解者 16例 (5 5 .1% ) ,部分缓解 13例 (44 .9% ) ,其中PVP不成功 1例 ,再经血管内栓塞化疗疼痛减轻 ,所有患者无严重并发症发生。结论 椎体恶性肿瘤经PVP和 (或 )血管内栓塞综合治疗可获得很好的近期疗效 。
Objective To evaluate the efficacy of percutaneous vertebroplasty(PVP) and endovascular chemotherapy and embolization for the treatment of vertebrae malignant tumors. Methods Twenty nine patients (male 16, female 13) had 40 vertebrae malignant tumors, including 28 patients with 37 vertebrae metastases and 1 patient with multiple myeloma involving 3 vertebrae. The primary foci were esophageal cancer, lung cancer, colon carcinoma, hepatic cancer, stomach cancer, breast cancer, kidney cancer and 2 of unknown. All the patients showed moderate or severe thoracic and lumbar pain with 2 patients of spinal cord dysfunction. Eighteen cases with 26 vertebrae were performed PVP only, 11 cases with 16 vertebrae were undergone endovascular chemotherapy and/or embolization. Results After treatment among 29 patients, 16 had CR(55.1%), 12 had PR(41.4%), 1 was unsuccessful with PVP but pain was relieved by endovascular therapy. No complication occurred.Conclusions PVP and PVP combined with endovascular therapy may have an excellent efficacy for vertebral malignant tumors, with relief of pain obviously and prolong the patient's life.
出处
《介入放射学杂志》
CSCD
2003年第1期39-42,共4页
Journal of Interventional Radiology
关键词
椎体
转移性肿瘤
栓塞
经皮椎体成形术
治疗
Vertebrae
Metastases
Neoplasm
Embolization
Percutaneous vertebroplasty
