摘要
目的 比较静脉应用胺碘酮与毛花甙C控制快速心房颤动 (简称房颤 )伴充血性心力衰竭(心衰 )患者心室率的即时效应及安全性。方法 4 6例房颤患者 ,心室率≥ 12 0次 /min ,心功能Ⅱ级以上(NYHA)。采用随机方式分组 ,分别静脉应用胺碘酮、毛花甙C。结果 胺碘酮、毛花甙C组控制房颤快速心室率的总有效率分别为 81 0 %和 60 9% (P <0 0 5 ) ;心室率平均下降幅度分别为 3 5 %和 2 5 % (P <0 0 1) ;平均起效时间分别为 (2 3 1± 8 2 )min和 (5 0 7± 10 4 )min (P <0 0 1)。胺碘酮组有 1例出现症状性低血压 ,1例出现Ⅰ°房室传导阻滞 ,无心衰加重表现。结论 静脉应用胺碘酮能迅速、安全。
Objective To evaluate the efficacy and safety of intravenous amiodarone and lanatoside C for the treatment of rapid ventricular rate in patients with atrial fibrillation and congestive hear filure.Methods Forty six patients with rapid atrial fibrillation,ventricular rate≥120 beats/minute,cardiac function≥second grade(NYHA),were randomly divided into two groups.The two groups were introvenously administered amiodarone and lanatoside C,respectively.Results The total efficacy on controlling rapid atrial fibrillation was 81 0% and 60 9% in amiodarone group and lanatoside C groups,respectively.Ventricular rate decreased by 35% and 25%,respectively.The mean response time was (23 1±8 2)minutes and (50 7±10 4)minutes,respectively.In amiodarone group,one patient developed symptomatic hypotension,and one had the first degree atrioventricular conduct block without worsening of congestive heart failure.Conclusion Amiodarone is safe and rapid in the treatment of rapid ventricular rate in patients with atrial fibrillation and congestive heart filure.
出处
《中华急诊医学杂志》
CAS
CSCD
2003年第3期188-190,共3页
Chinese Journal of Emergency Medicine
