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光子治疗联合前列地尔及α-硫辛酸治疗2型糖尿病周围神经病变临床疗效评价 被引量:9

Clinical Efficacy Evaluation of Photon Treatment Combination of Alprostadil and A-lipoic Acid in the Treatment of Type 2 Diabetes Peripheral Neuropathy
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摘要 探讨光子治疗联合前列地尔及α-硫辛酸治疗2型糖尿病周围神经病变的临床疗效。将2型糖尿病周围神经病变患者79例随机分为对照组(n=38)和试验组(n=41)。对照组采取降血压、降血脂、控制血糖、抗血小板聚集等常规治疗及前列地尔10μg加入0.9%氯化钠注射液10m L静脉推注,1次/d。试验组在对照组治疗基础上给予Carnation-11光子治疗仪对患者两侧足部进行照射治疗,并采用ɑ-硫辛酸注射液20ml加入0.9%氯化钠注射液100m L静脉滴注,1次/d。疗程均为两周。比较两组患者治疗前后的临床疗效及神经传导速度。试验组总有效率(90.24%)明显高于对照组(76.32%,P<0.05),试验组神经传导速度显著提高(P<0.05)。光子治疗联合前列地尔及α-硫辛酸治疗2型糖尿病周围神经病变有显著的临床疗效。 To explore the photon treatment of united front,and alpha lipoic acid treatment the clinical effect of the treatment of type 2 diabetes peripheral neuropathy,79 patients with type 2 diabetes peripheral neuropathy were randomly divided into control group( n = 38) and experimental group( n = 41). Control group to fall blood pressure,fall hematic fat,control blood sugar,antiplatelet aggregation and other conventional treatment and top ten mu g to join with 0. 9%sodium chloride injection 10 ml of intravenous injection,1 / d. Patients in the control group treatment were given Carnation-11 photon therapeutic apparatus based on radiation therapy for patients on both sides of the foot and the ɑ-thioctic acid injection 20 ml and adding 0. 9% sodium chloride injection 100 ml intravenous drip,1 / d. A course of two weeks. Compare two groups of patients before and after treatment the clinical curative effect and nerve conduction velocity. Treatment group total effective rate( 90. 24%) is significantly higher than the control group( 76. 32%,P <0. 05),nerve conduction velocity trial group increased significantly( P < 0. 05). The photon treatment of united front,and alpha lipoic acid in the treatment of type 2 diabetes peripheral neuropathy has significant clinical effect.
出处 《激光杂志》 北大核心 2015年第9期162-164,共3页 Laser Journal
关键词 糖尿病周围神经病变 前列地尔 Α-硫辛酸 光子治疗 Diabetic peripheral neuropathy Alprostadil Alpha lipoic acid The photon treatment
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  • 1Kovrazhkina E A.[Demyelinating polyneuropathies in patients with diabetes mellitus and chronic alcoholic intoxication]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinsko? promyshlennosti Rossi?sko? Federatsii, Vserossi?skoe obshchestvo nevrologov [i] Vserossi?skoe obshchestvo psikhiatrov . 2012
  • 2Winkler Gábor,Kempler Péter.[Pathomechanism of diabetic neuropathy: background of the pathogenesis-oriented therapy]. Orvosi Hetilap . 2010
  • 3VolchegorskǐiIA,Rassokhina LM,Miroshnichenko IIu,et al.An-tihypoxic effect of 3-hydroxypyridine and succinic acid derivatives and their nootropic action in alloxan diabetes. Eksperimental naia i Klinicheskaia Farmakologiia . 2011

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