摘要
目的:探讨不孕女性焦虑障碍对体外受精-胚胎移植(IVF-ET)后妊娠结局的影响。方法:采用汉密尔顿焦虑量表(HAMA)对160例IVF-ET不孕女性患者进行焦虑程度测评及分析,根据患者焦虑程度分为A、B两组,A组105例,轻度或中度焦虑;B组55例,重度焦虑。比较分析两组获卵数、2PN受精率、优胚率、取消率、胚胎种植率、临床妊娠率、异位妊娠率及早期流产率等。结果:B组患者的获卵数、2PN受精率、优胚率、临床妊娠率均显著低于A组,差异有统计学意义(t=3.388,χ~2=7.650,6.265,4.859;P<0.05)。两组的取消率、胚胎种植率、异位妊娠率及早期流产率差异无统计学意义(P>0.05)。结论:焦虑障碍可对IVF-ET结局产生不良影响,临床上应高度重视患者的焦虑程度,进行恰当的心理干预及治疗以改善IVF-ET妊娠结局。
Objective:To investigate the effect of anxiety disorder of infertile women on the pregnancy outcomes of in-vitro fertilization-embryo transfer(IVF-ET).Methods:Hamilton Anxiety Scale(HAMA)was used to evaluate and analyze the degree of anxiety of 160 women undergoing IVF-ET,according to patients’ anxiety degree,all cases were divided into A and B group:A group included 105 cases with mild or moderate anxiety,B group included 55 cases with severe anxiety.Several key parameters of the two groups,included the number of retrieved oocyte,2 PN rate,high qualified embryo rate,cancellation rate,embryo implantation rate,clinical pregnant rate,ectopic gestation rate and early abortion rate were compared and analyzed.Results:The retrieved oocyte number,2 PN rate,high qualified embryo rate,clinical pregnant rate of group B were significantly lower than those of group A(t=3.388,χ~2=7.650,6.265,4.859;P<0.05).The cancellation rate,embryo planting rate,ectopic pregnancy rate and early abortion rate were not statistically significant between the two groups(P>0.05).Conclusion:Anxiety disorder can have adverse effects on the outcome of IVF-ET,the patient’s anxiety level should be grasped clinically,and proper psychological intervention and treatment should be carried out to improve the pregnancy outcome of IVF-ET pregnancy.
作者
周晓景
王芳
ZHOU Xiaojing;WANG Fang(Reproductive Center,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,China)
出处
《中国健康心理学杂志》
2019年第2期208-210,共3页
China Journal of Health Psychology
基金
2016年度河南省医学科技攻关计划项目(编号:201602359)
