摘要
首先利用开环聚合的方法 ,制备了聚乳酸 -聚乙二醇嵌段共聚物 .然后以此为基材 ,采用乳化溶剂蒸发法 ,制备了聚乳酸 -聚乙二醇嵌段共聚物微球 ,分别研究了聚合温度、聚合时间和聚乙二醇的分子量等对共聚物的特性粘数 [η]的影响以及稳定剂、乳化剂、共聚物 [η]、搅拌速度及油 /水比对共聚物微球的影响 .
PLA-PEG block polymer was prepared by opening ring polymerization.The effects of the temperature,time of polymerization and the molecular weight of PEG were studied.A series of microspheres were made from PLA-PEG block polymer by emulsification evaporation technique.Effects of the stabilizer,the emulsifier,the molecular weight of copolymer,the speed of stir and the rate of oil/water on the size of microspheres were also disscussed.
出处
《同济大学学报（自然科学版）》
EI
CAS
CSCD
北大核心
2003年第2期191-195,共5页
Journal of Tongji University:Natural Science
基金
上海市科技发展基金资助项目 (0 0 2 3 12 0 2 4)
上海市重点基础研究资助项目 (0 2DJ 14 60 1)
