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十二指肠胃反流的研究 被引量:4

A STUDY OF DUODENOGASTRIC REFLUX
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摘要 目的 :本文旨在探讨生理性DGR发生的规律及正常参数值 ,对DGR与慢性浅表性胃炎的关系进行了研究。方法 :1 8例无任何临床症状的健康自愿者 ,1 6例慢性浅表性胃炎患者 ,用Bilitec 2 0 0 0行胃内 2 4h胆汁监测。结果 :生理性DGR胆红素光吸收值 >0 .1 4的总时间百分比 ,均值为 1 0 .4± 9.88,95 %参考值正常上限值为 35 .6 %。慢性浅表性胃炎组与健康对照组胆汁反流各项指标比较 ,无显著性差异 (P >0 .0 5)。结论 :正常健康人群在直立、仰卧、餐时、餐后不同阶段具有不同的十二指肠胃反流 ,睡眠时反流较其他阶段明显增多 (P<0 .0 5) ,且个体差异较大。正常健康对照组与慢性浅表性胃炎比较 ,无显著性差异 (P >0 .0 5) ,胃炎是否与胆汁相关 。 Objective:The aim of this study was to investigate the rhythm and normal parameters of physiologic duodenogastric reflux (DGR), and study the relationship between DRG and chronic superficial gastritis. Method:Sixteen patients with chronic superficial gastritis and eighteen healthy control all accepted 24-hour intragastric bile monitoring by Bilitec 2000.Results: The average of total fraction time of physiologic DGR bilirubin was 10.4±9.88, the upper limits for physiologic bile reflux are a percentage of total time of bile reflux of 35.6% (95th percentile with threshold 0.14). There was no significant difference of all kinds of bile reflux values between chronic superficial gastritis and healthy control ( P >0.05). Conclusions:Healthy persons have different reflux in different phases (upright, supine, meal and post prandial), and the bile reflux in sleeping increases more than that in the other phases ( P <0.05); There is variance in each person.There is no significant difference of the bile reflux between chronic superficial gastritis and healthy control. We should further study whether the gastritis is correlated with reflux.
出处 《中国内镜杂志》 CSCD 2003年第2期24-26,共3页 China Journal of Endoscopy
关键词 十二指肠胃反流 研究 胆汁 测定 胃炎 Duodenogastric Reflux 24hr Bile Monitoring Gastritis$$$$
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