摘要
目的 :观察低分子肝素治疗进展性缺血性脑卒中的疗效。方法 :将病程在 72 h内的 77例进展性缺血性脑卒中患者 ,随机分为低分子肝素 (L MWH)治疗组及常规治疗对照组 ,治疗组在常规治疗基础上 ,加用 L MWH5 0 0 0 IU,2次 / d腹壁皮下注射 ,疗程 7d治疗前后检测凝血常规、血小板 ,于治疗前、治疗后 3d、7d、2 1d进行神经功能缺损评分 ,2 1d时进行疗效评定。结果 :治疗组总显效率 6 8.4 % ,优于对照组 4 8.7% ,P<0 ,0 5 ;治疗后 7d、2 1d神经功能缺损评分明显下降 ,与对照组相比有显著差异 ,P<0 .0 5 ,且无明显不良反应。结论 :L MWH治疗进展性缺血性脑卒中近期效果较好 。
Objective:To investigate the efficacy of low molecular weight heparin(LMWH) in treating advanced ischemic stroke Methods:77 cases with ischemic stroke were divided into two groups randomly The treatment group was given 5000IU LMWH two times a day,besides routine therapy The control group was treated by routine therapy The treatment course was seven days Before and after treatment,the routine blood test,palatelet count and nervous function evaluation were checked up and the efficacy was analyzed Results:The efficacy rate in the treatment group was 68 4%,while the efficacy rate in control group was 48 7% The significant difference was found between the two groups( P <0 05) The situation of nervous function was remarkably improved in seven and 21 days after treatment in treatment group as compared with that in control group( P <0 05) No side effect was found in the two group Conclusion:A good efficacy is obtained in treating advanced ischemic stroke with LMWH However,the selection of cases should be considered
出处
《华夏医学》
2003年第1期21-22,共2页
Acta Medicinae Sinica
关键词
低分子肝素
进展性缺血性脑卒中
疗效
low molecular weight heparin
advanced ischemic stroke
efficacy
