摘要
目的 :探讨各型肺母细胞瘤的临床病理特点、鉴别诊断及预后。方法 :复习 3例肺母细胞瘤的病历资料并进行组织形态学、免疫组织化学观察和随访。结果 :3例均为女性。 2例成人型患者均 34岁 ;左、右下叶各 1例 ,镜下均为双相型 ,以具有胚胎特征的上皮和间叶组织构成。另 1例儿童型者发生于 3岁幼儿的膈胸膜上 ;肿瘤呈囊实性 ,囊内披覆纤毛柱状上皮 ,上皮下为具有横纹肌、软骨等分化的肉瘤组织。结论 :肺母细胞瘤是一种高度恶性的肿瘤。成人型多发于 30岁以上 ;儿童型多发于6岁以下。要正确组织分型并应与肺的癌肉瘤。
Objective: To investigate the clinicopathologic features , differenterial diagnosis and prognosis of pulmonary blastoma. Methods: 3 cases of pulmonary blastoma were reported with history records , light microscopic observation and immunohistochemical study. Results : 3 cases were all female, two adults (both 34 years old ) and one child. Histologically, two adults were all biphasic type , consist of epithelial and mesenchymial tissues with embryonal charactristics. For the 3 year old child , the tumor arose from pleura, it was cystic and solid , in the cystides, sarcomatous tissues which had rhabdiod and cartilaginous differention were covered with ciliated columnar epithelium. Conclusion : Pulmonary blastoma is a malignancy with poor prognosis, the adult type occured most commonly over 30 years , while the children type under 6. It should be distinguished from pulmonary adenocarcimoma and carcinosarcoma.
出处
《河北医学》
CAS
2003年第1期6-9,共4页
Hebei Medicine
关键词
肺母细胞瘤
临床病理学
诊断
治疗
预后
Pulmonary blastoma
Pathologic diagnosis
Immunohistochemistry
