摘要
目的:研究中药复方“五虎汤”大鼠灌胃后尿中的挥发性成分。方法:采用气质联用的方法对大鼠给药前后的尿液进行分析。结果:在给药大鼠的尿液中检测到18个与空白尿液相区别的成分,鉴定了14个,其中的7个成分在复方中也同时检测到。结论:检测到的区别成分可能来源于中药五虎汤,其中的一些成分与中药五虎汤的药效相关。
Objective: To identify the volatile components in rat urine after oral administration of 'Wu-Hu-Tang'(WHT). Method: GC-MS technique was applied to analyzing urine samples. Result: Eighteen components were detected in the WHT-treated rat urine other than the corresponding control. Among them, 14 components were identified, and 7 were also found in the extract of WHT. Conclusion: The above detected components might be derived from WHT, and some of them are effective components of WHT.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2003年第2期147-149,共3页
China Journal of Chinese Materia Medica
基金
国家自然科学基金(39970885)
教育部优秀青年教师基金
辽宁省自然科学基金重大项目(2001101009)
