摘要
采用双抗体夹心ELISA法对 5 7例病毒性肝炎患者的IL -10进行了测定。结果 各组肝炎患者血清IL-10水平变化不同 ,慢性中 -重度组血清IL -10水平显著升高 (P <0 .0 5 ) ;而慢性轻度组血清IL -10水平显著降低(P <0 .0 5 ) ;其中急性肝炎组和慢性重型组血清IL -10水平变化不大 ,检测血清IL -10在判断病毒性肝炎患者肝脏损伤程度上有一定的价值 。
Objective: The serum IL-10 levels were determined in 72 patients with viral hepatitis by double antibody sandwich ELISA. Results: showed that the serum IL-10 levels in patients with any type of hepatitis were different way.The serum IL-10 levels were increased sequentially in patients with chronic moderate and serious degree hepatitis;and serum IL-10 levels were decreased sequentially in patients with chronic low grade.The serum IL-10 levels were normal in patients with actual hepatitis and chronic severe hepatitis. Our results suggested that the serum IL-10 levels could reflect the degree of liver damage in patients with hepatitis,and detecting IL-10 could predicting prognosis in patient with severe hepatitis.
出处
《海南医学》
CAS
2003年第2期5-6,共2页
Hainan Medical Journal
