摘要
目的探讨青年乳腺癌与中老年乳腺癌的临床特点和预后。方法回顾性分析湖南省肿瘤医院1987年 1月至 1991年 12月收治的 4 0 9例临床Ⅰ～Ⅲ期乳腺癌资料 ,将其分为青年组 (≤ 35岁 ) (A组 )和中老年组 (>35岁 ) (B组 )。A组 6 7例 ,B组 342例 ,比较两组的临床资料。结果临床Ⅱ期A组 (4 9.3%)少于B组 (6 4 .3%) (P <0 .0 5 ) ,Ⅲ期A组 (38.8%)多于B组 (2 4 .0 %) (P <0 .0 5 ) ;肿瘤大小、病理类型、淋巴结转移情况、雌孕激素受体状况、手术方式、综合治疗方式和生存率两组相比均无统计学差异 (P >0 .0 5 )。A组和B组的 3年、5年生存率分别是 90 .76 %、6 7.2 9%和 86 .0 0 %、71.90 %,两组比较无统计学差异 (P >0 .0 5 )。结论本研究提示青年乳腺癌一旦发现即采取积极治疗 ,可能取得与中老年乳腺癌一样的效果 。
ObjectivesTo explore the clinical features and prognosis of young and mid old women with breast cancers. MethodsFour hundred and nine patients with breast cancers of clinical stage Ⅰ～Ⅲ admitted in Hunan Provincial Tumor Hospital between Jan.1987 and Dec.1991 were analyzed retrospectively, including Group A:67 young patients(≤35 years) and Group B:342 older patients(>35 years).The clinical data of two groups were compared.ResultsThe incidence rate of stage Ⅱcancer in Group A(49.3%) was less than that of Group B(64.3%)(P<0.05);while the incidence rate of stage Ⅲ in Group A(38.8%) was higher than that of Group B(24.0%)(P<0.05).Besides, there were no statistically significant differences in the tumor size, pathological typing, metastasis of lymph nodes, conditions of estrogen receptors(ER) and progestogen receptors(PR), mode of operation, mode of comprehensive therapy and survival rate between two groups (P>0.05).Overall 3 year and 5 year survival rates were 90.76% and 67.29% in young patients ,as compared with those of 86.00% and 71.90% in older patients, no statistical significance existed between both groups(P>0.05).ConclusionOur study suggests that once breast cancers are found in young women, if prompt measure had been taken, efficiency similar to mid old patients with breast cancers would be obtained. The age is not an independent factor of affecting prognosis.
出处
《医学临床研究》
CAS
2003年第3期189-191,共3页
Journal of Clinical Research
