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骨髓基质细胞诱导为神经原及胶质细胞 被引量:21

Neurons and neural ganglia! cells induced from bone marrow stromal cells
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摘要 目的:发现一种新的方法代替雪旺细胞用来修复周围神经缺损。方法:从大鼠抽取骨髓在体外诱导为胶质细胞并做免疫组化。结果:骨髓基质细胞在体外培养数代,显示出极强的扩增能力,并在条件培养液的作用下分化为神经原及神经胶质细胞。结论:经论证,本实验在治疗中枢及外周神经疾病方面有重要意义。 AIM: To find a new way to replace of Schwann cells, to regenerate nerve. METHODS: The stromal cell of bone marrow was obtained from Wister rat. and inducted into glial cells in vitro, then use histochemistry stains. RESULT: We demonstrate that bone marrow stromal cells can be inducted into neuron and glial cells by using particular method. CONCLUSION: The result of this test have an important significance in treatment of diseases of central and peripheral nervous systems.
出处 《中国临床康复》 CSCD 2003年第2期227-228,T004,共3页 Chinese Journal of Clinical Rehabilitation
基金 国家973资助项目(1999054300)
关键词 骨髓基质细胞 神经原 神经胶质细胞 细胞分化 周围神经缺损 bone marrow cells cell differentiation cell culture
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同被引文献140

  • 1梅晰凡,范广宇,秦书俭,郑德宇,李德超.转化生长因子β和神经生长因子联合诱导成年鼠骨髓基质细胞分化为神经细胞的研究[J].中国临床康复,2004,8(26):5553-5555. 被引量:4
  • 2王亚平,牛宏,姜蓉,王勇,祝彼得.三七总皂甙对红系祖细胞增殖调控机理的研究[J].解剖学杂志,1996,19(2):138-147. 被引量:14
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