4Hurwitz HI,Fehrenbacher L,Hainsworth JD,et al.Bevacizumab in combination with fluorouracil and leucovorin:an active regimen for first line metastatic colorectal cancer.J Clin Oncol,2005,23 (15):3502-3508.
5Kabbinavar FF,Hambleton J,Mass RD,et al.Combined analysis of eficacy:the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer.J Clin Oncol,2005,23(16):3706-3712.
6Hurwitz H,Fehrenbacher L,Novotny W,et al.Bevacizumab plus irinotecan,fluorouracil,and leucovorin for metastatic colorectal cancer.N Engl J Med,2004,350(23):2335-2342.
7Saltz LB,Clarke S,Díaz-Rubio E,et al.Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer:a randomized phase Ⅲ study.J Clin Oncol,2008,26(12):2013-2039.
8Giantonio B,Catalano P,Meropol N,et al.Bevacizumab in combination with oxaliplatin,luorouracil,and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer:results from the Eastern Cooperative Oncology Group Study E3200.J Clin Oncol,2007,25(12):1539-1544.
9Fuchs CJ,Marshall J,Barrueco J.Randomized,controlled trial of irinotcean plus infusional,bolus,or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer:updated results from the BICC-C study.J Clin Oncol,2008,26(4):689-690.
10Wolmark N,Yothers G,O'Connell MJ,et al.Phase Ⅲ trial comparing mFOLFOX6 to mFOLFOX6 plus bevacizumab in stage Ⅱ or Ⅲcarcinoma of the colon:Results of NSABP Protocol C-08.J Clin Oncol,2009.27(18s):abstr LBA4.
