摘要
目的 :评价奥硝唑氯化钠注射液治疗口腔颌面部整形术后厌氧菌感染的疗效。方法 :以甲硝唑氯化钠注射液为对照 ,采用多中心随机对照方法 ,对两组间临床疗效和细菌清除率进行比较。结果 :奥硝唑氯化钠注射液与甲硝唑氯化钠注射液的临床治愈率分别为65 %和40 % (P<0 01) ,总有效率和细菌清除率无显著性差异(P>0 05)。结论 :奥硝唑氯化钠注射液治疗口腔颌面部整形术后厌氧菌感染效果显著。
OBJECTIVE:To evaluate the therapeutic effect of Ornidazole on the anaerobic infections after maxillofacial plastic surgery.METHODS:40patients suffering from anaerobic infections after maxillofacial plastic surgery were randomly divided into two groups.One group was treated with injection of Ornidazole,while another group treated with Metronidazole injection seved as control.The clinical effects and bacteria clearance rates were compared between two groups.RESULTS:The curative effect was65%in the trial group and40%in control group,which existed a significant difference(P<0.01).But there were no significant differences between two groups in total effective rate and bacteria clearance rate.CONCLUSION:It is efˉfective and safe to treat anaerobic infections after maxillofacial plastic surgery with injection of Ornidazole.
出处
《中国药房》
CAS
CSCD
2003年第4期228-229,共2页
China Pharmacy
