摘要
目的 :初步探讨马尾神经损害导致马尾神经综合征 ,神经根后根节的病理变化。方法 :取不同时间段的马尾神经综合征的模型的神经根的后根节 ,作HE染色对其内正常感觉神经元细胞记数。结果 :临床出现马尾神经综合征 1 / 2d ,将导致双侧后根节缺血水肿 ,节内神经元细胞坏死。结论 :后根节内的感觉神经元极敏感 ,极易坏死 ,是马尾神经损害顺行溃变的重要病理变化之一 ,是导致鞍区麻木、感觉障碍 。
Objective: To study the pathology of sacral spinal ganglion with cauda equina syndrome.Met hods: At the follow times (1/4d? 1/2d? 3d? 7d?15d),animals were given a let hal overdose of chloral hydrate and perfused intracardially with NS and 4% paraf ormaldehyde in cauda equina syndrome specimen. The sacral spinal ganglion was re moved .And it were put in fixative overnight, and serial 5μm coronal sections w ere HE staining, and optics microscope were used to observe number and pathology of pseudounipolar neuron of sacral spinal ganglion.Result: There were swollen o f spinal ganglion and necrosis of pseudounipolar neuron after cauda equina syndr ome. Conclusion:General injure of cauda equina lead to bilateral swollen of spinal ganglion and necrosis of pseudounipolar neuron in se quence and saddle hypoesthesia,and motor weakness in the lower extremities in as sociation with either bowel or bladder dysfunction.Not all criteria are required for the diagnosis to be established. Symptoms of urinary dysfunction and saddle hypo esthesia with varying degrees of motor and sensory loss in either of the extremi ties are ,however, necessary for the diagnosis. $$$$
出处
《中国矫形外科杂志》
CAS
CSCD
2002年第13期1317-1318,共2页
Orthopedic Journal of China
