摘要
目的 探讨血栓前体蛋白 (thrombusprecursorprotein ,TpP)在急性冠脉综合征的预测价值。方法 分别在健康人组 ,不稳定心绞痛组 (UA)、急性心肌梗死组 (AMI)和其他胸痛病人组 ,于发病 6小时内检测TpP、磷酸肌酸激酶同工酶MB(CK -MB)、肌钙蛋白I(cTnI) ,肌红蛋白 (Myo)。结果 AMI组TpP明显升高 ,与健康对照组 ,UA组和其他胸痛病人组比较有显著性差异 ,TpP在胸痛组 ,UA组和AMI组的阳性检出率分别为 37 5 % ,30 %和 92 3% ;而心肌损伤标志物在四组之间比较差异无显著性。另外 ,AMI组TpP灵敏度与CK -MB、cTnI、Myo的差异比 (OR值 )分别为 6、4、4。结论 TpP与常规心肌损伤标志物比较 ,对AMI更具早期预测价值。
Objective The change of TpP in Acute Coronary Syndrome.Methods Objects examined were composed of 4 groups:healthy controls,unstable angina,MyocardiaI Infarction,other chest pain,TpP,CK MB,cTnI,Myo of them are tested within 6 hours of onset respectively and the results were done with statistic analysis.Results TpP increased significantly in AMI as compared to the other three groups.The positive rates of TpP in other chest pain,UA,AMI are 37.5%,30%,92.3%,respectively,And in the group of AMI,the odds ratio(OR)of TpP compared with CK MB,cTnI,Myo are 6,4,4.Conclusion TpP is a good index in the carly prediagnose of Acute Coronary Syndrome.
出处
《中国实验诊断学》
2003年第1期14-15,共2页
Chinese Journal of Laboratory Diagnosis
