摘要
目的 :比较复方甘草甜素与肝炎灵治疗慢性乙型肝炎的疗效及不良反应。方法 :选择慢性乙型肝炎患者 87例 ,随机分成治疗组 4 4例 ,给予复方甘草甜素 10 0ml +5 % 2 5 0ml·d-1,ivgtt,1mon后改为复方甘草甜素片 5 0mg口服 ,tid ,连用 2mon为一疗程。对照组 4 3例 ,给予肝炎灵 4ml·d-1口服 ,3mon为一疗程。同时两组均配合使用常规治疗药物 ,治疗 2个疗程。结果 :疗程结束时 ,治疗组在临床症状、体征改善方面 ,以及在肝功能的改善方面均优于对照组 ,治疗组的总有效率为 90 .9% ,而对照组的总有效率为 5 5 .8% ,两者有显著的统计学意义 (P <0 .0 5 ) ,未见严重的药物不良反应。结论 :复方甘草甜素治疗慢性乙型肝炎 ,效果明显 ,疗效确切 。
AIM: To compare the efficacy and side effects between stronger Neo Minophagen C(SNMC) and caryophyllin. METHODS: 87 patients were randomly divided into two groups. 44 patients as a treatment group orally received 250 ml 5% glucose and 100 ml SNMC orally once a day for 1 month. Then the dose of SNMC changed to 50mg, tid for 2 months. 43 patients as a control group were given caryophyllin 4 ml·d -1 for 3 months. RESULTS: After completion of therapy, the clinical syndromes and the liver function of the treatment group were much better than that of control group. The general effective rate was 90.9 % in treatment group and 55.8 % in control group (P< 0.05 ). Side effects were not found. CONCLUSION: SNMC is effective agent in treatment of patients with chronic hepatitis B.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2003年第2期207-209,共3页
Chinese Journal of Clinical Pharmacology and Therapeutics
