摘要
非甾体类抗炎药(nonsteroidal antiinflammatory drugs,NSAIDs)具有良好的抗炎、退热、镇痛等作用,因其应用方便,效果明显,目前在全世界范围内得到广泛应用,尤其在老年人群中的应用更为广泛。但NSAIDs使用过程中产生的不良反应不容忽视,仍应引起临床重视。本文总结近十年来与NSAIDs相关的文献,对NSAIDs的产生过程、运用情况、分类方法、作用机制及不良反应致病机制等方面进行简要介绍,重点综述NSAIDs所致胃肠道不良反应的临床特点及防治策略,旨在提高临床对NASIDs的认识,并为进一步的研究提供线索及方向。
NSAIDs are widely used clinically, especially in old patients because of their excellent effects on anti-inflammation, defervescence, analgesia and so on. However, the side-effects of NSAIDs cannot be ignored. In this paper, we reviewed the literatures on NSAIDs in the past ten years, and made a brief introduction NSAIDs background, classification, mechanisms of both the effects and the side-effects. We also summarized the clinical characteristics of gastrointestinal adverse reactions caused by NSAIDs and the ways how to prevent the side-effects in the elderly.
出处
《中华老年病研究电子杂志》
2017年第4期22-27,共6页
Chinese Journal of Geriatrics Research(Electronic Edition)
