摘要
将鲫鱼暴露于浓度分别为 0 .0 0 16、0 .0 16、0 .16mg·L-1的PCP溶液 15d ,同时做空白对照 ,测定鲫鱼肝脏的SOD、GSH、MDA以及NO、NOS等指标。试验结果表明 ,0 .16mg·L-1组处理的鲫鱼第 13天全部死亡。与对照相比 ,在 0 .0 0 16mg·L-1浓度下 ,PCP提高了鲫鱼肝脏MDA和NO含量 ,GSH含量降低 ,SOD活性被抑制 ,NOS活性有所升高。在 0 .0 16mg·L-1浓度组 ,PCP对几个指标的影响比 0 0 0 16mg·L-1组大 ,与对照相比 ,具有显著差异 。
Pentachlorophenol-induced oxidative stress in liver of crucian carp was studied by comparing crucian carps in the control with those exposed to solutions with pentachlorophenol(PCP) concentration at 0.001 6,0.016 and 0.16 mg·L -1 separately for 15 days in SOD,GSH,MDA,NO and NOS in livers of the crucian carps.The results show that the carps in the 0.16 mg·L -1 treatment all died on 13th day;that in the 0.001 6 mg·L -1 treatment,PCP increased MDA and NO contents in livers of the carps and decreased GSH content,and SOD activity was inhibited whereas NOS activity stimulated;and that in the 0.016 mg·L -1 treatment,the effects of PCP on these indexes were more significant than in the 0.001 6 mg·L -1 treatment.These data indicate that exposure to PCP may lead to generation of free radicals,depletion of antioxidants and peroxidation of lipids,thus resulting in oxidative stress in livers of the crucian carps.
出处
《农村生态环境》
CSSCI
CSCD
北大核心
2003年第1期40-42,共3页
Rural Eco-Environment
基金
"8 63"国家高技术研究发展计划项目 ( 2 0 0 1AA640 60 1-4 )
