摘要
目的:总结嗜铬细胞瘤的诊治体会。方法:回顾性分析50例嗜铬细胞瘤的临床资料。结果:82％的患者有高血压史,平均病程28个月。血儿茶酚胺和尿香草基苦杏仁酸增高者分别为68％,84％。B超、CT定位诊断阳性率为90％,95％;术前诊断正确率为94％。良性嗜铬细胞瘤43例,恶性嗜铬细胞瘤7例,其中:2例临床病程为良性而病理诊断为恶性,1例初次发病即为恶性,4例为复发性。2例恶性嗜铬细胞瘤伴肝转移放弃治疗,1年后死亡。结论:患者延迟就诊,基层医生对该病缺乏认识是导致误诊的主要原因。复发性嗜铬细胞瘤有很高的恶变性,应尽可能完整切除肿瘤,并加强随访。
Purpose:To summarize the experience in diagnosis and treatment of pheochromocytoma. Methods: Fifty cases of pheochromocytoma were analyzed retrospectively. Results: 82% of the patients had hypertension; the mean history of all the patients was 28 months. The positive sensitivity of blood catecholamine was 68% ,and urinary VMA was 84%. The accurate rate of tumor localization by B-ultrasonography, CT was 90%, and 95%. The preoperative correct diagnosis was 94%. Forty three cases were benign pheochromocytoma (86% ),recurrent adrenal pheochromocytoma 6 (12%),and malignant pheochromocytoma 7,of them,2 cases were malignant pathologically, but clinical course was benign,one case was malignant at first diagnosis,and 4 cases were recurrent, 2 patients died of liver metastasis 1 year later after diagnosis. Conclusions; Recurrent pheochromocytoma was highly predisposed to be malignant,resection of tumor totally and long-term follow-up were recommended.
出处
《临床泌尿外科杂志》
2003年第4期207-209,共3页
Journal of Clinical Urology
