摘要
目的 :了解 ICU获得性肺炎的病原菌及耐药性情况 ,为临床防治提供依据。方法 :对本院 1998年 5月～ 2 0 0 0年 6月间获得性肺炎患者的痰标本进行细菌学的分离和耐药性分析。结果 :检出 2 5种 2 6 2株细菌 ,其中以 G- 杆菌为主 ( 79.8% ) ,其次是 G- 球菌 ( 11.8% )和念珠菌 ( 8.4 % )。 G- 杆菌中 ,非发酵菌占主导为 4 3.1% ,大肠埃希菌和肺炎克雷伯菌次之 ,分别为 16 .7%和 14 .4 %。 G+球菌中以凝固酶阴性葡萄球菌为主 ,为 83.9%。细菌呈多重耐药趋势 ,在 G- 肠杆菌科中 ,4 0 %为产超广谱β-内酰胺酶株 ( ESBL s) ,在凝固酶阴性葡萄球菌中耐苯唑西林者 ( MRSCN)为 2 6 .9%。结论 :ICU获得性肺炎病原菌以非发酵菌占主导并呈多重耐药趋势。其感染菌谱的变迁和耐药率的普遍升高 ,应引起广泛重视 。
Objective: To study for bacteria of nosocomial pneumonia and the change of drug resistance in comprehensive intensive care, to offer basis for prevention and treatment Methold: The bacteria were isolated from expectoration of nococomial pneumonia and drug resistence were analysed during 1998～June 2000 Results: There are 25 species 262 strains bacteria were isolated The main pathogens of nosocomial pneumonia were Gram negative (79 8%), Gram positive coccus(11 8%) and fungi(8 4%) Nonfermeners in Gramnegative bacteria was the major one (43 1%), then Escherichia coli (16 7%) and Klebsiella pneumoniae(14 4%), In Gram positive bacteria, Staphylococcus of coagulase negative (83 9%) was main germs Among Staphylococcus of coagulase negative MRSCN were 26 9% 40% Enterrobacteriaecae were extended spectrum β lactamase(ESBLs) Conclusions: The main pathogen of nosocomial pneumonia was nonfermenters in ICU, the most bacteria were multidrug resistant Understanding the kinds of clinical bacteria changeing and bacteria resistance rate increasing are the prerequisite of useing antibiotics rationally
出处
《中国微生态学杂志》
CAS
CSCD
2003年第2期109-110,共2页
Chinese Journal of Microecology
