期刊文献+

高游离脂肪酸血症是胰岛素抵抗在高血压发病机制中的作用环节之一 被引量:5

Elevated Circulating Free Fatty Acid Levels Play a Role in the Pathogenesis of Hypertension in Insulin Resistant States
下载PDF
导出
摘要 胰岛素抵抗在高血压发病机制中的作用日益得到重视 ,但其具体意义尚不清楚。 The role of insulin resistance in the pathogenesis of hypertension is more important than before,but its meaning has not been known yet.The present article reviewed and summarized the role of plasma elevated insulin and free fatty acid levels in hypertension and analysed its possible mechanisms.
作者 王顺
出处 《心血管病学进展》 CAS 2003年第3期201-205,共5页 Advances in Cardiovascular Diseases
关键词 高游离脂肪酸血症 胰岛素抵抗 高血压 发病机制 胰岛素 游离脂肪酸 free fatty acid endothelium insulin resistance hypertension
  • 相关文献

参考文献27

  • 1邵建华,高妍,袁振芳,马红.游离脂肪酸抑制大鼠肝细胞胰岛素受体和胰岛素受体底物-1酪氨酸磷酸化[J].中华内分泌代谢杂志,1999,15(6):342-345. 被引量:15
  • 2邵建华,高妍,袁振芳.游离脂肪酸对大鼠骨骼肌细胞胰岛素受体与胰岛素受体底物1的表达和酪氨酸磷酸化的影响[J].北京医科大学学报,1998,30(5):425-428. 被引量:18
  • 3Landsberg L. Diet,obesity and hypertension: on hyperthesis involving insulin,the sympathetic nervous system,and adsptive thermogenesis[ J]. Q J Med,1986,236:1081-1090.
  • 4Grekin R J, Vollmer AP, Sider RS. Presser effects of portal venous oleste infusion. A proposed mechanism for obelity hypertension [ J ]. Hypertension, 1995,26:193-198.
  • 5Wilde DW,Massay KD,Walker GK,et a1. High-fat diet elevstes blood pressure and cerebrovascular muscle Cs^2+ current[ J ]. Hypertension ,2000,35:832-837.
  • 6Stojiljkovie MP,Zhang D ,Lopes HF,et al. Hemodynamic effects of lipids in humans [J]. Am J Physiol.2001,280 : R1674-R1679.
  • 7Fagot-Csmpagns A, Balkau B, Simon D, et al. High free fatty scid concentration :an independent risk factor for hypertension in the Paris Prospective Study [ J ].Int J Epidemiol, 1998,27(5) :808-813.
  • 8Sheu WH ,Jeng CY ,Shieh SM ,et al. Suppression of nonesterified fstty scid concentrations by insulin in patients with hypertension [ J ]. Chin Med J, 1995,56 :367-372.
  • 9Msision P,Byrne CD,Nicholas-Hsles C,et sl. Hypertension and its trestment influence changes in fasting nonestertfied fatty acid concentrations : a link between the sympathetic nervous system and the metabolic syndrome[J] ? Metabolism ,2000,49 ( 1 ) :81-87.
  • 10Egan BM, Hennes MMI, Stepiakowski KT,et al. Obesity hypertension is relate more to insulin′s fatty acid than glucoee action[J]. Hypertension ,1996,27(part2) :723-728.

二级参考文献5

  • 1Han D H,Diabetes,1997年,46卷,1761页
  • 2Borkman M,N Engl J Med,1993年,328卷,238页
  • 3Sun X J,Nature,1991年,352卷,73页
  • 4Boden G,J Clin Invest,1994年,93卷,2438页
  • 5Sun X J,Nature,1991年,352卷,73页

共引文献27

同被引文献55

引证文献5

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部