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乳腺癌新辅助化疗若干问题的讨论 被引量：20

Neoadjuvant chemotherapy for breast cancer:its use and limitations
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摘要 新辅助化疗有缩小原发肿瘤病灶、降低分期、减少播散及体内药敏试验的作用 ,已成为局部晚期乳腺癌的标准治疗 ,但对较早期可手术乳腺癌的应用仍在探讨之中。现综述新辅助化疗在乳腺癌的应用及存在问题。
作者 郝春芳 江泽飞 宋三泰
机构地区 军事医学科学院
出处 《国外医学（肿瘤学分册）》 2003年第2期116-118,共3页 Foreign Medical Sciences (Cancer Section)
关键词 乳腺癌 新辅助化疗 蒽环类联合方案 紫杉类药物 HER-2基因 淋巴结浸润 核磁共振成像检查
分类号 R737.9 [医药卫生—肿瘤] R730.53 [医药卫生—肿瘤]
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参考文献18

  • 1Fisher ER, Wang J, Bryant J, et al. Pathobiology of preoperative chemotherapy: findings from the National Surgical Adjuvant Breast and Bowel (NSABP) protocol B-18 [J]. Cancer, 2002,95(4):681-695.
  • 2van der Hage JA, van de Velde CJ, Julien JP, et al. Preoperative chemotherapy in primary operable breast cancer: results from the European Organization for Research and Treatment of Cancer trial 10902[J]. J Clin Oncol, 2001,19(22): 4224-4237.
  • 3Newman LA, Buzdar AU, Singletary SE, et al. A prospective trial of preoperative chemotherapy in resectable breast cancer: predictors of breast-conservation therapy feasibility [ J ]. Ann Surg Oncol,2002,9(3) : 228-234.
  • 4Ezzat AA, Ibrahim EM, Ajarim DS, et al . High complete pathological response in locally advanced breast cancer using paclitaxel and cisplatin [J]. Breast Cancer Res Treat, 2000,62(3):237-244.
  • 5Buzdar AU, Singletary SE, Valero V, et al. Evaluation of paclitaxel in adjuvant chemotherapy for patients with operable breast cancer:preliminary data of a prospective randomized trial [ J ]. Clin Cancer Res, 2002,8(5): 1073-1079.
  • 6Smith IC, Heys SD, Hutcheon AW, et al. Neoadjuvant chemotherapy in breast cancer: significantly enhanced response with docetaxel[J]. J Clin Oncol, 2002,20(6): 1456-1466.
  • 7NSABP. The effect on primary tumor response of adding sequential Taxotere to Adriamycin and cyclophosphamide: Preliminary results from NSABP Protocol B-27 [ J ].Breast Cancer Res Treat,2001,69:210a.
  • 8Wenzel C, Locker GJ, Pluschnig U, et al. Phase Ⅰ/Ⅱ trial of weekly epidoxorubicin and docetaxel (wED) in the neoadjuvant and palliative treatment of patients with breast cancer [J]. Cancer Chemother Pharmacol, 2002,50(2): 155-159.
  • 9Gregory RK, Powles TJ, Salter J, et al. Prognostic relevance of cerbB2 expression following neoadjuvant chemotherapy in patients in a randomised trial of neoadjuvant versus adjuvant chemoendocrine therapy [J]. Breast Cancer Res Treat, 2000, 59(2): 171-175.
  • 10Estevez LG, Cuevas JM, Anton A, et al. Weekly docetaxel as neoadjuvant chemotherapy for stage Ⅱ and Ⅲ breast cancer: efficacy and correlative with biological markers in a phase Ⅱ, multicenter study [J]. Clin Cancer Res, 2003,9(2): 686-692.

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国外医学（肿瘤学分册）
2003年 第2期

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