摘要
目的:比较液基细胞薄层涂片(LCT)与传统宫颈巴氏涂片(CS),探讨LCT的优越性。方法:依据TBS诊断标准,对同一时期行宫颈病变筛查的妇女,随机做LCT或CS检查,部分行HPV检测及宫颈活组织检查,评价两种涂片方法的满意度、敏感度以及特异性。结果:LCT涂片不满意率为0.28%,低于CS(0.49%)。对ASCUS及LSIL的检出率,LCT分别为6.81%和1.62%;CS分别为4.42%和1.01%,LCT明显高于CS(P<0.01)。对HSIL的检出率,LCT为0.29%,CS为0.24%,二者没有明显差异(P>0.05)。HPV高危阳性的ASCUS病例,CINII-Ⅲ级检出率高于HPV高危阴性病例(17.4%和4.92%)。结论:采用LCT进行筛查,可提高宫颈细胞学筛查的满意度及敏感性。
Object: Approach superiority of Liquid-based cytology,in comparison with conventional cytology. Methods:Data from CS and LCT that were obtained in the same period ,some data from specimen detecting HPV and cervical biopsy,and assessed in terms of sensitivity,specificity and the percentage of unsatisfactory slides with strict TBS criteria. Results: The unsatisfactory rate of LCT was lower(0.28%) than CS(0.49%). The detection rates of ASCUS and LSIL was higher in the LCT group(6.81%,1.62%) than the CS group(4.42%,1.01%).There wasn't obviously difference in the detection of HSIL(LCT0.29%,CS0.24%).With ASCUS cases whose HPV were positive,there was an increase in the detection rates of CIN II-Ⅲ,in comparison with negative cases (17.4% vs. 4.92%). Conclusions: The use of Liquid-based cytology enhance the efficiency of cervical cytology screening.
出处
《内蒙古中医药》
2008年第8X期58-61,共4页
Inner Mongolia Journal of Traditional Chinese Medicine
