摘要
目的 探讨感染性眼内炎导致眼球丧失的相关危险因素。方法 对 1993年 2月～ 2 0 0 2年 12月收治的116例 (117眼 )感染性眼内炎患者进行回顾分析。结果 2 1例 (2 1眼 )行眼球摘除或眼内容物剜出 ,发生率为17 95 % ;其中视力无光感的眼内炎病例中眼球丧失的发生率是 80 % (P =0 .0 0 0 1OR =73.6 ) ;内源性眼内炎的发生率是 4 5 .4 5 % (P =0 .0 12 5OR =4 .6 9) ;眼球破裂伤的发生率是 4 1.6 7% (P =0 .0 0 31OR =6 .78) ;女性眼内炎的发生率是 35 .2 9% (P =0 .0 0 2OR =4 .4 8) ;前、后 5年眼球摘除或眼内容物剜出的发生率分别是 2 6 .5 3%和11 76 % (P =0 .0 4 0 )。结论 眼内炎病例中视力无光感、内源性眼内炎、眼球破裂伤及女性是导致眼球摘除或眼内容物剜出的危险因素 ;眼球摘除或眼内容物剜出的发生率逐年减少。
OBJECTIVE To identify risk factors leading to evisceration or enucleation after endophthalmitis. METHODS A retrospective analysis was performed on 116 consecutive patients (117 eyes) with endophthalmitis presenting to the PLA General Hospital between Feb 1993 and Dec 2002. Clinical variables were evaluated for association with an increased risk of evisceration or enucleation. RESULTS Twenty one (17.95%) patients underwent evisceration or enucleation during the study period. No light perception at presentation (P=0.0001, OR=73 6), endogenous endophthalmitis (P=0.0125, OR=4.69), rupture injury (P=0.0031, OR=6 78), and female sex(P=0.002, OR=4.48) were statistically significant factors associated with an increased incidence of evisceration or enucleation. The incidence of evisceration or enucleation tended to decline in the second half of the decade (13/49, 26.53% versus 8/68, 11.76% P=0.040). CONCLUSIONS No light perception at presentation, endogenous endophthalmitis, rupture injury, and female sex are statistically significant factors associated with an increased incidence of evisceration or enucleation. There has been a significant decrease in the number of evisceration or enucleation related to endophthalmitis over the last decade.
出处
《中华医院感染学杂志》
CAS
CSCD
2003年第6期538-540,共3页
Chinese Journal of Nosocomiology
